1. What data in particular will be shared?
   Response - Individual participant data that underlie the results reported in this article, after de-identification (text, tables, figures, and appendices).
   


2. What additional supporting information will be shared?
   Response -  Study Protocol
   Response -  Statistical Analysis Plan
   Response - Informed Consent Form
   
   
3. Who will be able to view these files?
   Response - Researchers whose proposed use of the data has been approved by an independent review committee identified for this purpose.
   


4. For what types of analyses will this data be available?
   Response - Any purpose.
   


5. By what mechanism will data be made available?
   Response - Proposals should be directed to [thara@scarfindia.org].
   


6. For how long will this data be available start date provided 01-06-2028 and end date provided 01-06-2033?
   Response - Immediately following publication. No end date.
   


7. Any URL or additional information regarding plan/policy for sharing IPD? 
   Additional Information - NIL

INTREPID is a programme on the epidemiology of Psychoses in three sites in the Global South (India, Nigeria, Trinidad). With INTREPID, our ultimate, ambitious goal is to transform our knowledge of and responses to psychotic disorders globally. We plan to achieve this by (1) delivering novel research programmes on medium-term course and outcomes, homeless populations, and putative mechanisms of risk and relapse, and (2) implementing a structured set of activities in each setting to ensure findings inform the development, and ultimately testing, of bespoke interventions. Our programme will be guided by our lived experience teams in each setting. We wish to examine the underlying mechanisms and processes involved in varying presentations, higher rates, poorer outcomes, and patterns of physical health and mortality. Three putative mechanisms are of particular interest that may mediate and constitute the pathways between risks and the onset and outcome of psychoses: (1) stress sensitivity; (2) cognitive function; and (3) accelerated aging. We have fixed the cohort sample size in each site to be between 200 and 220. And an additional 20 cases and 20 controls experiencing homelessness will be recruited to help us identify the pathways to homelessness. Quantitative research method is used to understand how the course of psychoses and other outcomes differ between the sites. Qualitative research method is used to examine the profiles and needs of individuals with a psychotic disorder who are homeless and to examine pathways into homelessness in each setting. Appropriate statistical analysis methods will be used to analyse the collected data. The overall outcomes are the predictors of course of psychoses and how it affects living situations, interpersonal relationships, physical health, cognitive functioning, etc. with this study we expect to deepen and broaden our understandings of psychotic disorders and to inform the development of locally relevant humane, accessible, and effective services.