It is a prospective, open label, randomized control trial of parallel-groups to compare the efficacy of erector spinae plane block versus conventional pharmacological therapy in successfully alleviating abdominal pain of patients with pancreatitis in an Emergency Department. Patients of pancreatitis with Abdominal pain will be examined and history will be taken, patients meeting inclusion criteria will be included in the study after taking consent for the study. Patients meeting any one of the exclusion criteria will be excluded from the study. After that, randomization to different study arm patient will be allcocated, randomization will be done by a pre-formed computer generated randomization table and allocation concealement will be done by SNOSE technique. Our primary objective is to assess the efficacy of successful pain relief (more than 50% reduction in pain score by DVPRS from presentation or DVPRS less than 4 in both arm at one hour in both ESPB arm and conventional pharmacological therapy (CPT) arm. Secondary objectives are to assess pain score assessment at different time interval up to 6 hours or up to 24 hours if patient remains in ED, pain free interval in both arm, timing of rescue therapy, drugs or procedure related adverse events in both arm, reasons for failure of therapy in both arm, efficacy of image acquisition and optimization and interpretation by different performers on Likert scale, patient feedback based on Likert scaling regarding preference of therapy he or she would opt for in next visit.