Knee OA is a leading cause of functional limitation among older adults. There are a number of treatment options available, both pharmacological and non-pharmacological, in combination. Non-pharmacological treatment options include exercises, physical modalities, orthoses, interventions or surgery (at late stages).

Exercises are known to be associated with better outcomes when supervised, which is not practical at most times. So, a proper structured home-based exercise  program might be more practical in these patients. These measures are believed not only to reduce pain, but also improve the functional outcome of the patients. Hence, we want to know the functional outcomes of a proper structural home based exercise in Knee Osteoarthritis patients.

Also various factors are known to affect the response to the available treatments for individuals with Knee OA. An understanding of such predictors for a successful outcome will help to provide a broader perspective to health practitioners. Thus, we will also try to find predictors for successful outcomes in these patients.

All patients coming to AIIMS, PMR-OPD with the complaint of knee pain will be thoroughly examined after taking detailed history for possibility of enrolling in the study. Those who have Knee OA as per revised ACR criteria for early diagnosis of Knee OA, will be advised plain X ray of knee AP (weight bearing position) and skyline view to know the severity as per Kellgren & Lawrence (KL) grading.  All patients with KL Grades of OA knee (TF) including those waitlisted for surgery more than 8 weeks, will be enrolled in the study after ruling out the exclusion criteria and after taking a written informed consent.

After enrolling in the study, all patients will be required to undergo a triple phase bone scan with single-photon emission computed tomography-computed tomography (SPECT/CT). 

All patients will also be asked to do a 6MWT to note down the distance walked by the patient in 6 minutes, which will indicate the status of function. All enrolled patients will also be asked to fill up the KOOS questionnaire.

The structured exercise program will comprise of aerobic/warm-up, strengthening exercises (quadriceps, hip extensors and hamstrings), stretching exercises (tendoachilles, hamstrings, quadriceps) and neuromuscular control exercises. After 2 weeks, all participants will be given a telephone call to reinforce the exercises and other advices, as well as to find out if they have any issues/doubts. They will be followed up physically after 4 weeks and will be required to undergo another 6MWT and to fill up the KOOS questionnaire. Last follow up will be done at the end of 8 weeks where 6MWT and KOOS questionnaire filling up is again done. A Patient Global Impression of Change (PGIC) will also be asked to be filled up by the patient at 8 weeks to know their overall status since the start of the study. Categories of ’very much improved’ and ’much improved’ in PGIC will be considered as successful outcome in our study.