Periodontitis is an inflammatory destructive disorder of the periodontal supporting structures, which is associated with microbial dysbiosis. Its primary features include the loss of periodontal tissue support , manifested through clinical  attachment loss , presence of periodontal pocket and radiographically alveolar  bone loss. The goal  of  regenerative periodontal therapy, is to restore the tooth supporting apparatus that has benn lost due to periodontal disease or injury . PRF is classified as a second generation platelet concentrate, as it is prepared as a natural concentrate without the addition of any anticoagulants. Platelet rich fibrin  is an easily prepared , autologous natural scaffold  harbouring a multitude of growth /differentiation factor. Vitamin C may lower the risk of periodontal diseases and even facilitate  healing  of the periodontium due to its strong antioxidant capacity that allows it to inactivate ROS that  damage structure and function of tissues.Surgical procedure is done after presurgical treatment ,that is scaling and root planning. After oral prophylaxis is done , 1 week follow up is done . After 1 week clinical parameters to be evaluated and surgery is performed in which OFD  with PRF  is done on one side and on the other side OFD  alongwith  ascorbic acid and PRF is injected on other side. Then flaps are approximated and then sutured . After that clinical and radiographic parameters are evaluated at 3 months and 6 months.