Dushtavrana is a chronic type of wound resulted from varied aetiology. In contemporary science, it can be clinically correlated to chronic ulcers. Varicose ulcers are one among chronic venous ulcers. Venous ulceration is the most severe & debilitating outcome of chronic venous insufficiency in the lower limbswhich affects the quality of life of an individual by pain, itching, altered appearance, loss of sleep, functional limitations. Venous disease is responsible for around 85% of all chronic lower limb ulcers in resource-rich countries. Community based prevalence is 0.1-0.3% in adults(2-4% in elderly).The general line of treatment includes conservative approach such as Bisgaard method, compression therapy, vaccum assisted dressing, hyperbaric oxygen therapy, antibiotics, NSAIDs and surgical interventions like Thiersch grafting and laser ablation have their own shortcomings. Nearly all venous ulcers can be healed, but even in those who have successful ablation or wear their stockings religiously, there is a 20–30% incidence of re-ulceration by 5 years.

            Sushruta has explained Shashti upakrama in which specific avastha of vrana chikitsa are highlighted. It includes shodhanartha & ropanartha upakrama like kashaya, varthi, kalka, sarpi, taila, rasakriya and avachurnana. Among them taila possess kaphavatagna, vranashodhana, lekhana  properties & are indicated in sadhyovrana, dushtavrana & dagdhavrana chikitsa. Lipid soluble drugs can penetrate more rapidly than water soluble drugs at the cell surface to enter into the circulation very quickly.

            Arjuna is mentioned as one among the drugs of Nyagrodadi gana which is having kashaya rasa, ruksha guna, sheetha virya and vranya properties which could be beneficial in dushtavrana. It has antioxidant, anti-inflammatory, analgesic, antimicrobial and antiviral properties. Pre-clinical study conducted on topical application of Terminalia arjuna showed significant effect in histopathology and in wound healing.