Electrolyte disturbances have important implications not only for patient management but also for identifying & better understanding of potential pathophysiologic mechanisms underlying COVID-19.  A single-center, retrospective, observational study will be carried out to find any correlation between the level of the electrolyte disturbances and the morbidity and mortality, acid base disturbances on admission & outcome, prognostic factors associated with disease progression & mortality risk in patients hospitalized in intensive care unit with severe Covid -19 disease

This study will follow the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) reporting guideline. Male & female patients 18-65 years old who were confirmed by the real-time PCR/Rapid antigen test on the respiratory tract samples as positive of SARS-CoV-2.

hospitalized in intensive care unit from 1 July 2020 until 31 October 2020 died and recovered with Covid-19 disease will be collected retrospectively & analyzed. 

Data on age, sex, laboratory values during admission (hemoglobin concentration, lymphocyte count, platelet count, arterial blood gas analysis, markers of inflammation, serum and urine creatinine, urea, serum and serum and urine electrolyte), comorbidities, sign and symptoms at presentation, vital signs, administered treatment (diuretics, electrolyte supplement), as well as the admission in ICU.