The term sinusitis is replaced by rhinosinusitis because sinusitis is often preceded by rhinitis and rarely occurs without concurrent nasal airway inflammation. Thus, the refers to inflammation of the mucosal lining of nose and paranasal sinuses. Chronic rhinosinusitis is very common condition and has been estimated to affect approximately 5-15% of general population. It is often very frustrating and difficult to treat therefore many patients have undergone with repeated courses of antibiotics, long term use of oral or topical steroids and multiple sinus surgeries increasing their risk of colonization with antibiotic resistant agent, various side effects of steroids and of surgical complications. Approximately 200000 U.S adult undergo sinus surgery per year for chronic rhinosinusitis, most commonly because of failing medical therapy. As far as economic impact is concerned, CRS accounts for substantial healthcare expenditure in terms of doctor’s visits, antibiotic prescribed, lost work days and missed school days. In unani literature there is no specific description of Waram-e-Tajaweef-e-Anf Muzmin (chronic rhinosinusitis) but the features described by unani physicians under nazla barid and nazla muzmin in various books corresponds with signs and symptoms of sinusitis.

Unani system of medicine provides abundance of single and compound drugs which can be given in nazla barid for longer duration without any known side effect.