The current study aims to establish clinical equivalence of Trutie® Ligating clips (Healthium Medtech Limited) to Ligaclip® ligating clips (Ethicon) in laparoscopic cholecystectomy and generate additional evidence on usage of Titanium metal ligating clips. The use of surgical clips is crucial in laparoscopic surgery/ cholecystectomy. Titanium ligating clips are a type of non-absorbable clip that are commonly used in laparoscopic cholecystectomy procedures to secure the cystic duct and cystic artery during gallbladder removal. These clips are made of a lightweight, durable metal and are designed to provide a secure and permanent closure of the ducts. In current study we plan to assess the clinical equivalence of both devices via incidence of bile leakage and bleeding after closure of cystic duct and cystic artery, assessment of intra and post-operative complications, adverse device reactions, and adverse events from day of surgery to 6 months post-operatively, time taken from initial incision to closure of wound, intraoperative handling of clips and clip applicator between the two groups using 5-point scale, number of clip breakage, failure to ligate, and malformed or deformed clips, Postoperative length of hospital stay, incidence of residual risks of ligating clips, time to recovery as measured by return to the normal day to day activities and quality of life using the Otago gallstones condition specific questionnaire. Clinical data obtained by this study will add value to the user’s decision to choose the titanium ligating clip in various surgeries.