-Early detection of severity of acute pancreatitis with help of markers Serum Calcium and Serum Lactate, which can be readily available in laboratories, which is not time consuming and does not require experts to interpret the values/reports. 

Study Hypothesis:

Hypocalcemia is consistent with severe acute pancreatitis and Lactate is a product of anaerobic metabolism of glucose and is generally considered to be a marker of tissue hypoxia. In addition, previous studies have also found that the presence of elevated arterial lactate levels reflects critical tissue hypoperfusion, which is strongly associated with increased morbidity and mortality in critically ill patients. A recent study has shown that elevated serum lactate is a new biomarker that could be an important tool in predicting poor outcomes of Acute Pancreatitis on admission, especially in predicting death. Thus, we assume that arterial lactate may be an important biomarker to stratify patients with Acute Pancreatitis. Hence, serum calcium and serum lactate (in mmol/L) can be useful to predict severity of cases early in disease onset as hypocalcaemia is found to be a poor prognostic marker and elevated lactate level is a marker of sepsis, tissue hypoxia and necrosis. Moreover much literature on serum calcium: serum lactate ratio levels have not been found.