Vitiligo is a cosmetic dermatological defect, but it has a very prominent social and psychological impact on the patient. It is a depigmenting skin disorder characterized by the selective loss of melanocytes, which in turn leads to pigment dilution in the affected area of the skin. The characteristic lesion is totally amelanotic, non-scaly, chalky-white macule with distinct margins. Vitiligo is a common dermatological as well as cosmetic and social problem with prevalence 1% to 2% of the world population .In India it is between 3% to 4%^. The incidence of vitiligo as reported by various workers in different cities of India can be 2.9% in Goa, 8.8% in Delhi. However most authors say that its incidence is around is 4% which is however definitely more as compared to worlds population of 1%. Several single and compound formulations have been used to treat vitiligo by many ancient Unani physicians, but some of them are not yet scientifically evaluated on modern parameters. Hence, this A Randomized, Parallel Group, Open Label, Active Controlled Clinical Study is planned to evaluate the Efficacy and Safety of Roghan-i-Baras in the Management of Baraá¹£ (Vitiligo). Participants fulfilling inclusion and exclusion criteria will receive either test or control drug as per randomization. In test group participants will start with Roghan-i-Baras and in control group participants will start with Methoxsalen 1% , for the duration of 16 weeks. Baseline and last follow up and laboratory investigations will be done. 

Statistical analysis : After completion of the study, data obtained will be analysed statistically by using an appropriate statistical test to evaluate the significance of results. p<0.05 will be considered significant.