Medodushti does not bear a direct reference as a disease entity in Brihattrayi, though it can be studied under the broad umbrella of Sthaulya or Medoroga, as a causative factor, aetiopathogenesis, signs and symptoms, treatment is similar for Medoroga and Medodushti.According to modern opinion, the amount of total cholesterol, triglyceride, LDL, VLDL, and HDL is abnormal in Dyslipidemia disorder. This is due to the abnormal metabolism of lipids and lipoproteins. Due to this, there is a possibility of various complex diseases like coronary heart disease (angina, ischemic heart disease, myocardial infarction) diabetes, cerebral-vascular disease, Hypertension, and atherosclerosis.In the present era, Diseases caused by improper lifestyles are more challenging. Medodushti (Dyslipidemia) is exclusively one of the lifestyle disorders because Excessive stress, lack of exercise, day sleep, junk food, canned food, soft drinks, high fatty diet, and continuous intake of high-calorie food items lead to medodushti (Dyslipidemia) and coronary artery diseases.Dyslipidemia is an established and modifiable risk factor for coronary artery disease.Drugs used in modern science to treat Dyslipidemia have several adverse effects like myopathy, the potential increase in serum transaminase levels leading to liver damage, nausea, bowel upset, etc.

More ever, drugs like statins, fibrates, resins, etc. are expensive and therefore hard for common men to purchase.So, it needs time to find out a safe and cost-effective treatment for Dyslipidemia from Ayurveda.

Most cases of dyslipidemia are due to the modern lifestyle full of sedentary lifestyles and unhealthy food habits.Cardiovascular Diseases (CVD) have a high disease burden in India. Dyslipidemia, a major CVD risk factor, requires effective management. Our review describes the efficacy of Vyoshadya saktu and tryushanadi guggulu in the management of medodhusti (Dyslipidemia). The prevalence of Dyslipidemia ranges from 25-30% in urban people and 15-20% in rural. It will be a single-center, nonrandomized, open‑clinical study. In this study, 60 clinically diagnosed patients of medhodhusti (Dyslipidemia) will be selected. Vyoshadya saktu will be given in doses of 50 gm saktu + 3-gram aushadhi churna three times a day with lukewarm water before a meal along with tryushanadi Guggulu in the form of vati 500mg each 2 vati four times a day for 90 days.  Statistical analysis will be done using Wilcoxon signed rank test will be using for the analysis of nonparametric data, while paired t-tests will be used for parametric data analysis.