Vatarakta is major disorder of Vata & Rakta. Acharya Caraka has classified in two types- 1. Uttana, 2. Gambhira. Signs and symptoms of Utthana Vatarakta are Kandu, daaha, rujaa, toda, sphurana and darkening of skin. The signs and symptoms of Gambhira Vatarakta are Shotha (inflammation), kaathinya, vedanaadhikya, daaha, toda, bheda, sphurana, paaka and joint deformity in later stage. When all the symptoms and signs of both the types are present it is called as Ubhayagat Vatarakta. Acharya Sushruta considers these as stages of Vatarakta instead of types.

On the basis of the symptomatology, Vatarakta can be correlated with the desease condition Gout. Gout is a rheumatic disease resulting from deposition of uric acid crystals (monosodium urate) in tissues and fluids within the body. This process is caused by an overproduction or under excretion of uric acid.

The drugs Amritadi Guggulu and Pinda Taila are among various drugs mentioned in ayurveda that help to treat Vatarakta. This study is aimed to establish their role in treating gout and establish their safety by assessing modern parameters.

The contents of these drugs are:

Amritadi Guggulu consists:

1. Guggulu (Resin of Commiphora mukul), 

2. Triphala (fruit pilp of Terminalia chebula Retz, Terminalia bellirica, Emblica officinalis),

3. Guduchi (Stem of Tinospora cordifolia)

4. Danti (Root of Baliospermum montanum)

5. Trikatu ( Fruit of Piper longum, Piper nigrum, Zingiber officinale)

6. Vidanga ( Fruit of Embelia ribes)

7. Tvak (Stem bark of Cinnamomum zeylanicum)

8. Trivrit (Root of Operculina turpethum)

Pinda Taila consists:

1. Mdhuchhishta (Beewax), 

2. Manjistha, (Root of Sida cordifolia)

3. Sarjarasa (Resin of Shorea fobusta Gaertn. f.)

4. Sariva (Root of Hemidesmus indicus).

5. Til taila (Sesmum oil)

The objective of the trial is to validate and establish the clinical efficacy of these classical ayurvedic formulations on scientific basis to establish its safety in the treated subjects.