Patients undergoing breast surgery experience marked acute pain postoperatively. The axillary component of the surgery is responsible of the majority of this pain.When the postoperative pain is not controlled well, this leads to both psychological and physiological negative consequences. While effective control of the acute pain suppresses the surgical stress response and decreases the opioids and general anesthetics needs, that leads to preservation of the immune response. In addition, regional anesthesia can reduce the stress response caused by surgical trauma.Opioid based analgesic techniques are associated with hyperalgesia, tolerance and predisposition to chronic pain. Fascial plane blocks are emerging as novel analgesia techniques for breast surgery with favorable pain scores, improved patient satisfaction and quality of recovery with additional advantage of opioid sparing being reported in literature. The practice of taking up breast surgeries as day care procedures favor administrating analgesic techniques with minimal residual or adverse effects Interfascial blocks score over regional anesthetic techniques such as PVB as they have no risk of sympathetic blockade, intrathecal or epidural spread.