In the current era anesthesia is required for almost all surgeries that includes amnesia, analgesia, muscle relaxation and homoeostasis. Ideal induction agent for General Anaesthesia should have hemodynamic stability, minimal respiratory side effects, rapid clearance, lack of pain on injection, rapid return of consciousness. Induction is the most stressful moment of general anaesthesia. Commonly used induction agents are propofol, thiopentone, etomidate and ketamine. Increase in hemodynamic instability is more prominent in hypertensive patients, many times profound decrease in BP is observed. Propofol produce nitric oxide and cause bradycardia and hypotension due to reduction in preload and afterload. This study is aimed at comparing haemodynamic responses associated with anaesthetic induction with propofol and sodium thiopentone in hypertensive patients.

Hypertension is an modifiable risk factor cardiovascular morbidity and mortality. Less than half of those who has hypertension are diagnosed with hypertension others are left undiagnosed. Aetiology of hypertension is a complex

interaction between genetic and Pathophysiological mechanisms which involves multiple systems. Both lifestyle modification and pharmacological therapy are effective in lower blood pressure. Hypertension can primary

(essential hypertension) or secondary hypertension.

In this study hemodynamic responses of propofol and thiopentone in hypertensive is compared. Blood pressure, Heart rate and SPO2 will be measured at regular interval after giving anyone of the drugs. These data will be used compared and the efffect of both drug on hemodynamics in hypertensive patient.