1. What data in particular will be shared?
   Response - Individual participant data that underlie the results reported in this article, after de-identification (text, tables, figures, and appendices).
   


2. What additional supporting information will be shared?
   Response -  Study Protocol
   Response -  Statistical Analysis Plan
   Response - Informed Consent Form
   Response - Clinical Study Report
   
   
3. Who will be able to view these files?
   Response - Anyone
   


4. For what types of analyses will this data be available?
   Response - Any purpose.
   


5. By what mechanism will data be made available?
   Response - Proposals should be directed to [dr.raghavi96@gmail.com].
   


6. For how long will this data be available start date provided 01-01-2023 and end date provided 01-01-2024?
   Response - Immediately following publication. No end date.
   


7. Any URL or additional information regarding plan/policy for sharing IPD? 
   Additional Information - NIL

^·              Lower segment cesarean section (LSCS) may result in significant postoperative pain, which can negatively impact ambulation, breastfeeding, and even maternal bonding. Pain after LSCS has a somatic component arising from nociceptors within the surgical wound and a visceral component originating from muscles.Inadequate postoperative analgesia after cesarean delivery delays ambulation with subsequent increased risk of thromboembolism, and harms motherbabyrelationship⁽¹⁾ .Goal standard for postoperative pain is opioids whether administered systemic or neuraxial but it is associated with manyside effects such as nausea, vomiting, pruritus, constipation, and respiratory depression⁽²⁾. Multimodal approach of postoperative analgesia which combines parenteral analgesics with regional analgesic techniques may enhance analgesia of each component and decrease its side effects.⁽³⁾

^·              Transversus abdominis plane (TAP) block represents one of the most widely used regional analgesic techniques and important component of multimodal approach for postoperative analgesia.⁽⁴⁾Transversus abdominis plane (TAP) is a neurovascular plane between the internal oblique muscle and the transversus abdominis muscle through which pass the nerves supplying the anterolateral abdominal wall⁽⁵⁾.Application of the local anesthetics in this plane will produce myocutaneous sensory block between T6 and L1 (TAP) block which is suitable for pain relief in abdominal surgeries⁽⁶⁾.TAP block was described for the 1st time by Rafi in 2001; he called the technique as refined abdominal field block. TAP block hasbeen used successfully as an important element of multimodal postoperative analgesia for many abdominal procedures such as cholecystectomy, gynecological laparoscopy, appendectomy, nephrectomy, and cesarean delivery⁽⁷⁾.Establishment of TAP block requires injection of large dose of LA in this relatively vascular plane which leads to potential neurotoxic plasma level of the LA ,specially during pregnancy which increases susceptibility of the pregnant women to local anesthetic toxicity.⁽⁸⁾

^·              Ropivacaine is longer acting than lignocaine and has a documented better safety profile than bupivacaine. It is common practice nowadays to use ropivacaine for nerve blocks and fascial plane blocks.  For regional anaesthesia, local anaesthetics alone provide good operative conditions but have shorter duration of post-operative analgesia. Hence, various adjuvants such as opioids, clonidine and ketamine are added to local anaesthetics to achieve a quick, dense and prolonged block, but their use is limited by side effects such as nausea, vomiting and pruritis.⁽⁹⁾

·      Dexamethasone is highly potent, long-acting glucocorticoid with analgesic, antiemetic, and anti-inflammatory properties, and when used as adjuvant in peripheral nerve blocks, increases the duration of analgesia with minimal side effects and has an added advantage in decreasing postoperative nausea and vomiting (PONV)⁽¹⁰⁾. Dexamethasone when added as anadjuvant to Ropivacaine in ultrasound guided transversus abdominis plane block enhanced the duration of analgesia and decrease total rescue analgesic requirement.

·      The presence of N-methyl -D -aspartate receptors in skin and muscles have led to the use of Magnesium sulphate.Magnesium helps to regulate the amount of intracellular calcium  and is known to be able to control pain. Magnesium sulphate (MgSO4 ) has analgesic, antihypertensive, anaesthetic sparing effects when used systemically^(11,12).ln recent times, MgSO4 has been commonly used as an adjuvant to neuroaxial block, various peripheral nerve blocks as well as plane blocks.

·      Thus, this study aims to compare the effects of dexamethasone and Magnesium sulphate as an adjunct to Ropivacaine in Transverse Abdominis Plane (TAP) block as post-operative pain management in patients undergoing Ceserean section.