Abortion is defined as Termination of pregnancy by any means before the fetus is viable. Abortions will be done up to 24 weeks pregnancy Medical Termination of Pregnancy [MTP] Act, enacted by the Indian parliament came into effect from 1 April 1972 and new amendment of 2021.  Presently MTP can be performed on Medical, Eugenic, Humanitarian and Social grounds, Terminating a pregnancy in 2nd trimester is a bigger danger to both the mother and foetus as compared to a first trimester pregnancy. A majority of the abortions in second trimester are carried out because of foetal abnormalities and sometimes maternal complications. Out of the different methods of termination, medical methods are believed to be safer and more effective as compared to the surgical approaches. Intravaginal misoprostol and intracervical Foley catheter are the most preferred methods. Few researchers claim intravaginal misoprostol whereas others believe intracervical Foley catheter to be more effective and few researches have speculated that if the both methods are combined will give best results.

Hence, our study is aimed to compare the efficacy of misoprostol versus combination of Foley catheter and misoprostol in second trimester medical termination of pregnancy.  OBJECTIVES: To Compare the efficacy of misoprostol versus Foley and misoprostol combination in second trimester medical termination of pregnancy.

Data collection method: Pregnant women attending the OPD of GIMS for second trimester MTP that is 12+1 weeks to 24 weeks of gestation and who will fulfil inclusion and exclusion criteria were selected for the study. Ultrasound examination was used for the date confirmation and their eligibility to enter into the study. Selected patients were admitted to obstetrics ward and procedure will be planned. Complete evaluation of each patient was done at admission. Detailed history as well as clinical findings of medical and obstetric examination was recorded.