1. What data in particular will be shared?
   Response - All of the individual participant data collected during the trial, after de-identification.
   


2. What additional supporting information will be shared?
   Response -  Study Protocol
   
   
3. Who will be able to view these files?
   Response - Anyone
   


4. For what types of analyses will this data be available?
   Response - For individual participant data meta-analysis.
   


5. By what mechanism will data be made available?
   Response - Proposals should be directed to [geetamanojkamal@gmail.com].
   


6. For how long will this data be available start date provided 12-06-2022 and end date provided 30-06-2023?
   Response - Beginning 3 months and ending 5 years following article publication.
   


7. Any URL or additional information regarding plan/policy for sharing IPD? 
   Additional Information - NIL

All patients in this study will be subjected to detailed pre-anaesthetic evaluation which includes: Present complaints, drug history, past history of surgical procedure under regional anaesthesia, history of nausea, retching or vomiting within the preceding 24 hrs, any major medical illness and drug history. Complete general physical examination and ASA grading will be done.  All investigations including complete blood profile, random blood sugar, blood urea, serum creatinine, coagulation profile, serum electrolytes, urine analysis, HIV, HB_s Ag, Chest X-Ray PA view and ECG will be done prior to surgery. 

The night before surgery, all patients will be given orally omeprazole 20 mg, ranitidine 150 mg, and alprazolam 0.25 mg and advised to remain nil by mouth as per standard fasting protocol. On arrival of the patient in the operation theatre, the standard ASA non-invasive monitors like electrocardiogram (ECG), non-invasive blood pressure (NIBP) and peripheral oxygen saturation (SpO₂) will be applied and the baseline vital parameters (Heart rate, SpO₂, Blood pressure (systolic, diastolic, mean arterial pressure) will be recorded. The peripheral intravenous cannula will be secured with 18/20 G on the dorsum of the hand and lactated ringer (RL) solution will be started. The patients’ randomization will be done by computer-generated random number table and group allocation will be done by sealed opaque envelope method, which will be opened just before induction of anaesthesia.

The patient of both groups will be pre-medicated with Midazolam 0.05 mg/kg intravenously (IV) and fentanyl 2µg/kg IV. After preoxygenation for 3 minutes with 100% oxygen, anaesthesia will be induced with propofol 2-3 mg/kg IV till loss of eyelash reflex and no response to jaw thrust and. The airway will be secured 3 minutes after administration of atracurium 0.5 mg/kg IV by one of the airway devices as per study groups after application of 2% lignocaine jelly. The size will be chosen according to body weight. Both devices will be fixed by tapping the tube over the chin. 

Anaesthesia will be maintained with an oxygen/air mixture with Sevoflurane (0.6 to 2%) and Inj atracurium 0.1mg/kg using a closed circuit with a circle absorber. The patients will be ventilated with a tidal volume of 6-8 ml/kg at a respiratory rate between 14 and 16 bpm required to maintain normocapnia. During maintenance of anaesthesia, we will record oxygen saturation, HR, BP, end-tidal volume, peak inspiratory pressure, oropharyngeal leak pressure, number of airway manipulations required, and the airway quality by performing neck auscultation and airway complications. At the end of the surgery, anaesthetic agents will be discontinued, and Inj neostigmine 0.05mg/ kg along with Inj glycopyrrolate 0.01mg/kg will be given to reverse the action of muscle relaxation. After the return of adequate spontaneous respiration and muscle power, the device will be removed once the patient is awake.