TITLE OF DISSERTATION A CLINICAL ASSESSMENT TO EVALUATE THE EFFICACY OF YASHTYADI KWATH AND SHUNTHYADI PINDI IN THE MANAGEMENT OF PRAKLINNA VARTMA WITH SPECIAL REFERENCE TO SQUAMOUS BLEPHARITIS Aim:To evaluate the efficacy of Yashtyadikwath and ShunthyadiPindi in Praklinnavartma w.s.r to Squamous Blepahritis. Objectives: 1. To study the etiopathogenesis of Praklinnavartma- Squamous Blepharitits from ayurvedic & modern point of view. 2. To study the effectiveness of YashtyadiKwath and ShunthyadiPindi in Praklinnavartmaw.s.r. to Squamous Blepahritis at both local and systemic levels. 3. To review the relevant literature on Praklinnavartma& Squamous Blepharitits in both Ayurveda & modern perspective. HYPOTHESIS :- 1. Null Hypothesis H0 :- There is no effect of Yashtyadi kwath and Shunthyadi Pindi in the management of Praklinnavartma w.s.r. to Squamous Blepahritis. 2. Research Hypothesis H1 :- There is a significant effect of Yashtyadi kwath and Shunthyadi Pindi in the management of Praklinnavartma w.s.r. to Squamous Blepharitis. MATERIAL AND METHODS: • Source of data § Patient fulfilling the criteria of inclusion will be screened and selected from OPD and IPD of Shalakya Tantra department of D Y Patil School of Ayurveda, Nerul, Navi Mumbai. § Method of collection of data § Patients of either sex will be selected based on symptoms of Praklinnavartma w.s.r. to Squamous Blepharitis § Patient willing to participate in the present trial through written informed consent. Diagnosis will be established on the basis of presence of following signs and symptoms. 1. Itching in eyes 2. Burning sensation in eyes 3. Pain in eyes 4. Swelling in eyelids 5. Lacrimation (Watering from eyes). 6. Dandruff like deposition (Scales) on eye lid margin. 7. Through Slit lamp examination - Presence of Scaling on lid margins, Congestion, Oedema of Eyelids.
1) Inclusive criteria - 1. Patients presenting with the clinical features of Praklinnavartma (Squamous Blepharitis) 2. Patient with in the age group between 18 to 60 years 3. Patients who are willing to undergo the respective treatment protocol. 2) Exclusive criteria - 1.Patients who are below 18 years and above 60 years are excluded. 2.Pregnant women and lactating mother. 3.Patients suffering from other systemic disease like Hypertension, Diabetes Mellitus, Tuberculosis and Asthma.Associated with psoriasis and other skin diseases. 4.Patients suffering from other ocular disorders like Ptosis, Corneal ulcers, Follicular conjunctivitis, Purulent Conjunctivitis, Trichiasis, Multiple styes, Tumors etc.
PINDI KRIYAKALPA :- v Kriyakalpa are basically the procedures that are described where medicated Ghee and Churna (powdered formulations) or paste made from churna are administered either directly or indirectly (above or around) the eyes as an effective treatment modality. v Pindi is one of the Kriyakalpa described in Sharangdhar Samhita along with Bidalak in addition to other Kriyakalpas viz. Tarpan, Putapaka, Seka, Anjan and Ashchyotan. v Pindi is modification of bidalak. in this paste of medicines are covered in a cloth are placed over the closed eyes. it is also called as ‘kavalika’.
CONTENT:- NAME | QUANTITY | FORM | Shunthi | 2gm | Churna | Nimbapatra | 2gm | Churna | Saindhav | 1 pinch | Churna |
SOP of preparation of Shunthyadi LepaPindi:- 1. Mix all these drugs with addition of water and cook this mixture till it get thick and attain paste (Kalka) like consistency. 2. Then place a clean cloth over both eyes and put the lukewarm paste (3-4gm) over the cloth. 3. Put this for 15-20 mins over the eyes. RAS PANCHAKA:-
DRUG | LATIN NAME | RASA | VIRYA | VIPAK | GUNA | KARMA | Shunthi | Zingiber officinale | Katu | Ushna | Madhura | Snigdha, Laghu | Vrishya, Sopha-Kapharuchihara, Vatodara, Swasa, Pandu, SlipadaNasini | Nimba | Azadirachta indica | Tikta, Kashaya | Sheeta | Katu | Ruksha, Laghu | Vranahar, Kushtahara | Sainshav | Rock salt |
Lavana | | | | | YASHTYADI KWATH :- Steps Of Preparation OF YASHTYADI KWATH :- ü Mix all the churna of the following drugs viz. Yashtimadhu, Guduchi, Triphala and Daruharidra in equal quantity. ü Prepare a Decoction (Kwath) of these drugs for internal administration. ü Drugs which are used are of Rasayana, Tridoshashamak, Netrarogahar, Kandughna, Vedansthapan properties. Content :- Name | Quantity | Form | Yashtimadhu | 2gm | Churna | Guduchi | 2gm | Churna | Triphala | 2gm | Churna | Daruharidra | 2gm | Churna | RAS PANCHAKA: DRUG | LATIN NAME | RASA | VIRYA | VIPAK | GUNA | KARMA | Yashtimadhu | Glycyrrhiza glabra | Madhura | Sheeta | Madhura | Guru, Snigdha | Sandhaneeya, Varnya, Kandughna, Shonitasthapana | Guduchi | Tinospora cordifolia | Kashaya, Tikta | Ushna | Madhura | Laghu, Snigdha | Balya, Dahahara, Kushthahara, Krimihara, Chakshushya | Triphala | Terminalia chebula Terminalia bellerica Emblica officinalis | Madhura, Amla, Katu, Tikta, Kashaya | Ushna | Madhura | Ruksha Sara | Chakshushya, Deepana, Varnaropana, Ruchikara, Medohara | Daruharidra | Berberis aristata | Kashaya, Tikta | Ushna | Katu | Laghu, Ruksha | Arshaghna, Lekshaniya, Kandughna | ASSESMENT CRITERIA :- • An assessment criteria is designed based on subjective parameters :- 1. Itching of eyelids (Kandu) 2. Burning sensation (Daha) 3. Lacrimation (Strav 4. Scaling on Lid margin (Klinnata) 5. Congestion of lid margin (Raga) 6. Lid margin Oedema (Shotha) 1) Itching of eyelids (Kandu) :- 0 | Absent | No Itching | 1 | Mild | Occassional itching sensation | 2 | Moderate | Intermittent itching sensation which requires rubbing of eye | 3 | Severe | Most of the time intolerable itching which would requiresignificant eye rubbing | 2) Burning sensation (Daha) :- 0 | Absent | No burning sensation | 1 | Mild | Occasional burning sensation | 2 | Moderate | Intermittent burning sensation | 3 | Severe | Most of the time burning sensation | 3) Lacrimation (Strav) :- 0 | Absent | No lacrimation | 1 | Mild | Occasionally, tear flow out of eyes | 2 | Moderate | Intermittent out flow of tears 4-5 times / day on exposure to wind or doing some work | 3 | Severe | Most of the time out flow of tears is present | 4) Scales formation (Klinnata) :- 0 | Absent | No Scales formation | 1 | Mild | Small quantity of Whitish material on lid margins | 2 | Moderate | Moderate quantity of whitish material on lid margins | 3 | Severe | Whitish material lead to sticking of the eyelid margins. | 5) Congestion of lid margin :- 0 | Absent | No Congestion | 1 | Mild | Congestion, visible on slit lamp examination | 2 | Moderate | Congestion, visible on torch light examination | 3 | Severe | Congestion, visibly evident ondirect inspection | 6) Lid Margin oedema (Shopha) :- 0 | Absent | No lid margin oedema | 1 | Mild | Lid margin oedema visible on slit lamp examination | 2 | Moderate | Lid margin oedema visible on torch light examination | 3 | Severe | Lid margin oedema visibly evident on direct inspection |
TREATMENT PROTOCOL :- SAMPLE SIZE | 50 PATIENTS | TREATMENT DAYS | 45 DAYS | PINDI KRIYAKALPA DAYS | DAILY FOR 7 DAYS THEN TWICE A WEEK | KAAL OF THE KRIYAKALPA | IN THE MORNING | KWATH | YASHTYADI KWATH | DOSE OF THE KWATH | 30ML | KAAL OF THE KWATH | TWICE A DAY BHOJANOTTAR | BIBLIOGRAPHY: 1.The Chaukhamba Ayurvijnan Granthamala 71, Sushruta Samhita of Maharshi Sushruta Volume III Edited with ‘Susrutavimarsini’ Hindi Commentary Along with Special Deliberation by Dr. Anant Ram Sharma Foreword by Acharya Priya Vrat Sharma. 2.Krishnadas Ayurveda Series Vol. 27, Vagbhata’sAstangHridayam Translated by Prof. K. R. Srikantha Murthy Volume III UttarSthana. 3.Krishnadas Ayurveda Series 54, Yogaratnakar with ‘Vaidyaprabha’ Hindi commentary by Dr. Indradev Tripathi and Dr. Dayashankar Tripathi. 4.Jaikrishnadas Ayurveda Series No. 58 Sarangdhar Samhita (A treatise on Ayurveda) By Sarangdhar, Translated in English by Ayurvedvidwan Prof. K.R. Srikantha Murthy. 5.Kashi Ayurveda Series 17, Cakradatta (Sanskrit text with English translation), A treatise on Principles and Practices of Ayurvedic Medicine, Edited and Translated by Priya Vrat Sharma. 6.The Chaukhamba Ayurvijnan Granthamala 80, BhaisajyaRatnavali of KavirajGovindadas Sen Edited with ‘Siddhiprada’ Hindi Commentary by Prof. Siddhi Nandan Mishra. |