FULL DETAILS (Read-only)  -> Click Here to Create PDF for Current Dataset of Trial
CTRI Number  CTRI/2022/08/045051 [Registered on: 30/08/2022] Trial Registered Prospectively
Last Modified On: 21/05/2026
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Preventive
Process of Care Changes 
Study Design  Randomized, Parallel Group Trial 
Public Title of Study   A clinical trial to evaluate the effectiveness of selected multicomponent nursing interventions on quality of life and birth outcomes of pregnant women  
Scientific Title of Study   A randomized controlled trial to evaluate the effectiveness of selected multicomponent nursing interventions on quality of life and birth outcomes of pregnant women. 
Trial Acronym   
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Annamma Sumon 
Designation  Nursing Tutor 
Affiliation  Government College of Nursing, Jodhpur 
Address  Medical & health department, Government College of Nursing, M.D.M. Hospital Campus, Jodhpur
Medical & health department, Government College of Nursing, M.D.M. Hospital Campus, Jodhpur
Jodhpur
RAJASTHAN
342003
India 
Phone  919950571178  
Fax    
Email  thomasannamma27@yahoo.com  
 
Details of Contact Person
Scientific Query
 
Name  Prof Dr Yogeshwar Puri Goswami  
Designation  Principal  
Affiliation  Geetanjali University, Udaipur  
Address  Geetanjali College of Nursing, Geetanjali University, Udaipur
Medical & health department, Geetanjali College of Nursing, Geetanjali University, Udaipur
Udaipur
RAJASTHAN
313002
India 
Phone  918854999060  
Fax    
Email  dr.puri01@gmail.com  
 
Details of Contact Person
Public Query
 
Name  Annamma Sumon 
Designation  Nursing Tutor 
Affiliation  Government College of Nursing, Jodhpur 
Address  Medical & health department, Government College of Nursing, M.D.M. Hospital Campus, Jodhpur
Medical & health department, Government College of Nursing, M.D.M. Hospital Campus, Jodhpur
Jodhpur
RAJASTHAN
342003
India 
Phone  919950571178  
Fax    
Email  thomasannamma27@yahoo.com  
 
Source of Monetary or Material Support  
Antenatal OPD, Umaid Hospital,siwanchi gate Jodhpur 
Antenatal OPD,Mathura Das Mathur Hospital, shastri circle Jodhpur 
Principal Investigator Nursing tutor Government College of Nursing, Mathura Das Mathur hospital campus, shastri circle, Jodhpur  
 
Primary Sponsor  
Name  Annamma Sumon Principal investigator 
Address  Government College of Nursing, Mathura Das Mathur hospital campus shastri circle, Jodhpur 
Type of Sponsor  Other [Self (Ph.D. Scholar-Principal Investigator)] 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 2  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Annamma Sumon  M.D.M. Hospital, Jodhpur  Shastri circle, Jodhpur Obstetric & Gynaecology Department, Antenatal O.P.D.
Jodhpur
RAJASTHAN 
919950571178

thomasannamma27@yahoo.com 
Annamma Sumon  Umaid Hospital, Jodhpur  Siwanchi Gate, Jodhpur Obstetric & Gynaecology Department, Antenatal O.P.D
Jodhpur
RAJASTHAN 
919950571178

thomasannamma27@yahoo.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Institutional Ethics Committee, Dr. SNMC, Jodhpur  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Healthy Human Volunteers  Pregnant women 
Patients  (1) ICD-10 Condition: O365||Maternal care for known or suspected poor fetal growth,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Intervention  Multicomponent Nursing Component  1. Pschoeducation (improvement in nutrition through out pregnancy, reduce stress by diversion therapy) 2. Antenatal Exercises daily for atleast 10 weeks 3. Jacobsons Progressive Muscle Relaxation Technique daily for atleast 10 weeks Duration of intervention- 10 weeks 
Comparator Agent  quality of life before and after receiving multi component nursing interventions   quality of life of control and experimental group 
 
Inclusion Criteria  
Age From  18.00 Year(s)
Age To  40.00 Year(s)
Gender  Female 
Details  1. Pregnant women who will be attending antenatal OPD in II trimester (21-24 weeks of gestation) at maternity hospitals, Jodhpur.
2. Pregnant women between the age of 18 - 40 years.
3. Pregnant women of primi or secundigravida status.
4. Pregnant women who will be able to read, write and understand Hindi or English or local language.
5. Pregnant women who will be willing to participate in the research study.
 
 
ExclusionCriteria 
Details  1. Pregnant women who will be having high-risk pregnancy.
2. Pregnant women with psychiatric illness such as severe stress and anxiety, mental retardation, depression, personality disorders etc.
3. Premature delivery prior to completion of the follow-up period.
 
 
Method of Generating Random Sequence   Stratified block randomization 
Method of Concealment   Sequentially numbered, sealed, opaque envelopes 
Blinding/Masking   Open Label 
Primary Outcome  
Outcome  TimePoints 
1. To assess and compare quality of life score after 10 weeks of follow-up in experimental and control group.  at 21-24 weeks of gestation and after 10 weeks 
 
Secondary Outcome  
Outcome  TimePoints 
nil  nil 
 
Target Sample Size   Total Sample Size="220"
Sample Size from India="220" 
Final Enrollment numbers achieved (Total)= "184"
Final Enrollment numbers achieved (India)="184" 
Phase of Trial   N/A 
Date of First Enrollment (India)   01/09/2022 
Date of Study Completion (India) 31/07/2023 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Date Missing 
Estimated Duration of Trial   Years="1"
Months="0"
Days="0" 
Recruitment Status of Trial (Global)
Modification(s)  
Not Applicable 
Recruitment Status of Trial (India)  Completed 
Publication Details
Modification(s)  
A Randomized Controlled Trial to Evaluate the Effectiveness of Multicomponent Nursing Interventions on Quality of Life and Birth Outcomes of Pregnant Women Indian Journal of Public Health 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - YES
  1. What data in particular will be shared?
    Response - Individual participant data that underlie the results reported in this article, after de-identification (text, tables, figures, and appendices).

  2. What additional supporting information will be shared?
    Response -  Study Protocol
    Response -  Statistical Analysis Plan
    Response - Clinical Study Report

  3. Who will be able to view these files?
    Response - Researchers whose proposed use of the data has been approved by an independent review committee identified for this purpose.

  4. For what types of analyses will this data be available?
    Response - For individual participant data meta-analysis.

  5. By what mechanism will data be made available?
    Response (Others) - 

  6. For how long will this data be available start date provided 07-12-2027 and end date provided 07-12-2030?
    Response - Beginning 9 months and ending 36 months following article publication.

  7. Any URL or additional information regarding plan/policy for sharing IPD? 
    Additional Information - NIL
Brief Summary  

“A RANDOMIZED CONTROLLED TRIAL TO EVALUATE THE EFFECTIVENESS OF SELECTED MULTICOMPONENT NURSING INTERVENTIONS ON QUALITY OF LIFE AND BIRTH OUTCOMES OF PREGNANT WOMEN AT MATERNITY HOSPITALS, JODHPUR (RAJASTHAN)”.

Background of the study

Pregnancy is a physiological event, and it creates an important burden and stress for the female body. The expectant mother experiences many anatomical, physiological, psychological and biochemical changes to meet developing fetal demands, to protect homeostasis, to prepare for birth and lactation. These changes can affect the quality of life (QOL) of pregnant women, affecting both maternal and infant health. Maternal stress may increase the level of corticotrophin releasing hormone (CRH) in pregnancy that might lead to premature delivery. This may in-turn prove fatal and result in harming the child itself 3.

According to SRS 2016-18 MMR of India is 113 and in Rajasthan MMR is 164. In 2018, Peri-natal mortality rate of India was 22 and in Rajasthan it was 26. In India neonatal mortality rate is 23 and early neonatal mortality rate is 18. Neonatal mortality rate is 26 and early neonatal mortality rate is 20 in Rajasthan 4.

AIM AND OBJECTIVES

AIM:

This study aims to evaluate the effectiveness of selected multicomponent nursing interventions on quality of life and birth outcomes of pregnant women at maternity hospitals, Jodhpur (Rajasthan).

PRIMARY OBJECTIVE:

1.     To assess and compare quality of life score after 10 weeks of follow-up in experimental and control group.

SECONDARY OBJECTIVES:

1.     To find out association of quality of life score with birth outcomes (birth weight, duration of pregnancy, mode of delivery and APGAR score) in experimental and control group.

2    To assess quality of life score of pregnant women (21-24 weeks of gestation) at recruitment and find out its association with demographic variables (age, habitat, qualification, marital status, type of family, occupation, family monthly income, dietary pattern, substance abuse, gravida status and biological variable).


 

MATERIALS AND METHODOLOGY

PLACE OF STUDY:

The study will be conducted at Maternity hospitals (Umaid Hospital and MDM Hospital), Jodhpur (Rajasthan)

STUDY POPULATION/ SAMPLE:

Pregnant women attending antenatal OPD in II trimester (21-24 weeks of gestation) at selected maternity hospitals, Jodhpur (Rajasthan) will be taken up for the study after obtaining a written informed consent.

RESEARCH APPROACH:

Quantitative experimental research approach will be used.

STUDY DESIGN:     

Open label Randomized Controlled Trial will be used for the study.

PERIOD OF STUDY:

 The study will start after the permission from IEC and will take approximately 12-14 months. Another two months will be required for analysis of data and writing the thesis.

SAMPLE SELECTION CRITERIA:

Inclusion Criteria:

•        Pregnant women who will be attending antenatal OPD in II trimester (21-24 weeks of gestation) at maternity hospitals, Jodhpur.

•        Pregnant women between the age of 18 - 40 years.

•        Pregnant women of primi or secundigravida status.

•        Pregnant women who will be able to read, write and understand Hindi or English or local language.

•        Pregnant women who will be willing to participate in the research study.

Exclusion Criteria:

·       Pregnant women who will be having high-risk pregnancy.

•        Pregnant women with psychiatric illness such as severe stress and anxiety, mental retardation, depression, personality disorders etc.

•        Premature delivery prior to completion of the follow-up period.


 

Variables under study-

•        Dependent variable:   Quality of life of Pregnant women and birth outcomes (birth weight, duration of pregnancy, mode of delivery and APGAR score)

•        Independent variable: Multicomponent Nursing Interventions

•        Attribute variable: Age in years, habitat, qualification, marital status, type of family, occupation, family monthly income, dietary pattern, substance abuse, gravida status, and biological variable.

Tool for data collection

•        The tool comprises of three parts: -

Part-I: Socio-demographic proforma and biological variable

Age in years, habitat, qualification, marital status, type of family, occupation, family monthly income, dietary pattern, substance abuse, gravida status, and biological variable (height of the pregnant woman, weight, Hb% and BMI)

Part-II: Quality of life scale standardized tool RAND 36- Item short Form Survey (SF-36)

Part-III: Birth outcomes: it will be collected after delivery of the newborn.

•        Newborn birth weight

•        Duration of pregnancy

•        Mode of delivery

•        APGAR Score of newborn at 5 minutes after birth

Intervention of the study

  1. Multicomponent nursing interventions include: -
    1. Psychoeducation (Nutrition, activities of daily living, danger signals during pregnancy & labour, body image & appearance, self-esteem, personal belief and thinking, emotional aspect, domestic and sexual violence, engagement in social events & activities, substance abuse, recreational activities, arrangements of facilities and various programmes run by government)
    2. Antenatal exercises (walking, pelvic floor exercise, ankle exercise, breathing exercise) 
    3. Relaxation techniques (Jacobson progressive muscle relaxation technique)

Data collection procedure

The study will be conducted in 4 phases: -

  1. Pre-test on quality of life after taking informed consent (21-24 weeks of gestation)
    1. Sociodemographic variables
    2. RAND 36- Item Short Form Survey (SF-36)

II.     Application of selected multicomponent nursing interventions to experimental group.

III.   Post-test assessment of quality of life (31-34 weeks of gestation)

A.    RAND 36- Item Short Form Survey (SF-36)

            IV.    Assessment of birth outcomes (after delivery of the newborn)

                           A.          Birth outcomes

 

 
Close