The clinical study was carried out in 35 patients of Vicharchika. from O.P.D. of Govt. Akhandanand Ayurveda college and hospital, Ahmedabad. Among all registered patients 30 patients completed the course of treatment and evaluated for improvements on signs & symptoms of Vicharchika. The observation charts with brief description of the both groups of treatments and obtained results along with the statistical analysis presented in the form of tables. The data analysis of 35 patients of Vicharchika showed that 40% patients belonged to the age group of 31-40yrs, 51.43% were female, 97.14% were Hindu, 54.28% patients were graduate, 94.28% were married, 40% patients were housewife, 57.14% were belonged to lower middle class. In Pradhana Vedana observation; Kandu, Vaivarnyata and Rukshata were observed in 100% patients, Raji observed in 94.3% patients, Daha observed in 37.14% patients, Pidika observed in 20% of patients and Strav observed in 2.8% patients. Majority 62.8% patients were having symptoms since 1-5yrs, 74.28% patients were having gradual onset, 48.57% patients had acute condition of disease, 97.14% patients were having Shushka type of Vicharchika, 80% patients were not having spreading nature of Vicharchika, 91.43% patients were not having family history, 60% patients were having allergic past history, 77.14% patients had allopathic medication for Vicharchika treatment. In Ahara 77.14% patients were having veg. diet, 88.6% patients were having Katu-Amla Rasa Sevana, 45.71% patients were having Vishamagni, 57.14% patients were having irregular dietary habit, 40% patients had Samasana, 82.86% patients were addicted to tea, 68.57% patients had Samyaka Nidra, 77.14% patients were having regular bowel habit, 62.8% patients were Madhyama Koshthi, 74.28% patients were having normal mental status. In Aharaj Nidana, in Viruddha Ahara; 65.71% patients were having fruit+Dugdha and 62.86% patients were having Khichadi+Dugdha. In Garishta Ahara; 60% patients had fermented food and 57.14% patients had curd preparation. In Asatmya Ahara; 80% patients were having garlic & onion, 74.28% patients were having new Annapana. In Viharaj Nidana; 45.71% patients were doing Vegadharana, 37.14% patients were using cold water for either Pan or Snana purpose and 37.14% patients had day sleep. In Manasika Nidana; 71.43% patients had Chinta and 14.28% patients had Shoka about their diseased condition. In Dashavidha Pariksha, 60% patients were having Vata-Pitta dominance in Prakriti, 65.71% patients were having Raja-Tama dominance in Manasa Prakriti, 80% patients were having Madhyama Sara, 85.71% patients were having Madhyama Samhanan, 82.86% Madhyama Pramana, 85.71% patients were having Madhyama Satmya, 62.86% patients were having Avara Satva, 77.14% patients were having Madhyama Abhyavaharana Shakti, 54.28% patients were having Madhyama Jarana Shakti, 74.28% patients were having Avara Vyayama Shakti, 80% patients were belonged to Yuva Vaya, 97.14% were belonged to Sadharana Pradesh. In lesion site, 82.8% patients were having lesion over lower extremities, 60% patients were having atopic type of eczema, 37.14% patients were having more than 4 lesions on the body, 54.28% patients were having lesion of 1-5cm in size, 51.43% patients were having disease in Sthanika part of body, 82.8% patients had asymmetrical pattern of lesion, 97.14% had 1 region score.
• EFFECT OF THERAPIES 1. Group A: Siravedhana Karma along with Gandhaka Rasayana In this, group 17 patients were registered; 15 patients were completed the course of treatment (2 sitting of Siravedhana Karma with 15 days gap between each sitting along with Gandhka Rasayana orally 5gm/day in divided dose) and 2 patients were dropout. Treatment provided highly significant result in Kandu, Raji and Vaivarnyata and not significant result in Pidika, Daha, Rukshata and Strav. In EASI criteria highly significant result observed in erythema, edema/papulation, excoriation and lichenification. In overall assessment of group A, 26.67% patients had moderate improvement, 60% patients had mild improvement, 6.67% patients noted no improvement. 2. Group B: Pracchan Karma along with Gandhaka Rasayana In this, group 18 patients were registered; 15 patients were completed the course of treatment (2 sitting of Pracchan Karma with 15 days gap between each sitting along with Gandhka Rasayana orally 5gm/day in divided dose) and 3 patients were dropout. Treatment provided highly significant result in Kandu, Raji, Vaivarnyata, Daha and Rukshata and significant result was observed in Pidika. In EASI criteria highly significant result observed in erythema, edema/papulation, excoriation and lichenification. In overall assessment of group B, 13.33% patients had marked improvement, 80% patients had moderate improvement, 6.67% patients had mild improvement.
Discussion In this part the observations of study, trial drug mode of action, trial Karma mode of action and obtained result of both groups discussed with logical reasoning and brief description. Role of various factors and Nidana in Dosha Prakopa and manifestation of disease are discussed.
Summary & Conclusion This part comprises summary of all conceptual and clinical study briefly. The conclusion and interpretation drawn through the basis of study.
CONCLUSION A good conclusion is the determination established by investigation in various ways and it reviews the key points of dissertation and explain if the information is relevant, applicable or related to study as a whole. From observation and found results followed point were obtained and concluded that: Vicharchika, a type of Kshudra Kushtha; due to similarity in symptoms it can correlated with eczema. In Kushtha Chikitsa, Raktamokshana Karma is indicated as a line of treatment. In this study along with Raktamokshana Karma, Gandhaka Rasayana has been taken from Ayurved Prakash. No side effect or adverse effect was observed in both groups in present study. The therapy is very effective in treating Vicharchika. In this study null hypothesis (H0) and alternative hypothesis (H1) is rejected; alternative hypothesis (H2) accepted. Alternative hypothesis (H2): Raktamokshana performed with Pracchan is more effective in compare to Siravedhana in the management of Vicharchika (Eczema). On the basis of results of research study, it can be concluded that Pracchan Karma provides better result than Siravedhana in management of Vicharchika. It is due to maximum patients are having Alpa Sthangata Vicharchika and Pracchan Karma is mainly used to treat Alpa and Anavgadh Kushtha as per Samhita.
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