The number of obese people in Asia touching epidemic levels costing government millions of dollars in public health care. Now a days due to change in the life style and erratic dietary habits, a major chunk of the populations prefers to take junk food with less nutritive value associated with high risk factors for developing hyperlipidemia.

                        Hyperlipidemia means excess of lipids in the blood. Lipids are not water solube. They float in the blood and can attach themselves to the walls of the arteries causing atherosclerosis. As these atherosclerotic deposits or plaques, grow may sometimes trigger the formation of clots that block the flow of blood. If a clot obstructs one of the narrow coronary arteries it results into myocardial infarction, or heart attack.

                        Hyperlipidemia is associated with increased mortality and predisposes to the development of many diseases like diabetes, hypertension, myocardian infraction, gall bladder disease and certain forms of cancer. It can be viewed as a consequence of the interaction of environmental factors and the individual’s genetic substrate in particular with susceptibility genes. These genes enhance the storage of fat when food is limited and cause increased risk of hyperlipidemia when food is abundant and energy expenditure is reduced.

                        There are a number of appetite suppressing drugs and other formulations in modern medicine but these drugs do not work until and unless they are used continuously. More over some of them are having known side effects. To avoid this, Ayurveda has tried to develop a number of drugs but till today no such combination has been evolved which can cure this disorder. For the management of this disorder a lot of work has been done using a number of herbal drugs. Terminalia Bellerica has reduced the level of lipids in hypercholesterolemic rabbits (1) Garlic was found as lipid lowering agent in a study conducted in Germany on 261 patients (2) Gum guggulu was found effective in estrogen induced hyperlipidemia in chicks (3) In a similar study guggulu has been found effective in lowering serum lipids (4) In another study Albizzia Lebbek saponins have been found to be hypocholesterolemic (5) Amla has been found as hypocholesterolemic agent prevents premature atherosclerosis.

                        Keeping this view in mind present study is aimed to evaluate the clinical effect of Ayurvedic formulation on Hyperlipidemia.

                        Proposed study will be based on clinical study of Ayurvedic formulation which contains multi ingredients. The efficacy of these herbs on hyperlipidemia will be studied. This study will be able to produce an effective low cost and short duration treatment for hyperlipidemia.

                        Due to awareness of patent rules it will be beneficial not to disclose actual formulation of research plan.