A thorough pre anaesthetic evaluation will be done 24 hours prior to the procedure. All patients will be assigned to LFJ intraarticular PRP injection or RFA of medial branch nerve. The evaluation of the enrolled patients will be done by experienced Orthopedician and the diagnosis will be based on physical examination, radio imaging (MRI) and diagnostic block of L3/L4-L5/S1 LFJ with 0.5% Bupivacaine.  Standard monitoring with electrocardiography (ECG), automated NIBP (noninvasive blood pressure), and pulse oximetry (SpO₂) will be done for intraoperative monitoring.

Randomization of the participants into two groups id done by using sealed shuffled opaque envelope technique.

Participants will be divided into two groups:-

GROUP 1:-Those who are receiving intraarticular PRP injections

GROUP 2:- Those who are receiving RFA of medial branch nerve

This will be a double blinded study. In both groups, all procedures will be performed by the same experienced pain physician. The only unblinded personnel in this study is the primary pain physician. Patients will be unblinded after the 6 months follow up or if requested before that time.

Intraarticular Diagnostic blocks:

Patients in prone position, under fluoroscopy and under strict aseptic conditions, a 22G needle is inserted until it is contacted at the edge of the LFJ. Adequate needle positioning is confirmed by injecting 0.3 to 0.5ml of contrast. Once position is confirmed, 1ml of 0.5% bupivacaine is injected into LFJ.

Radiofrequency Denervation:

All RFA procedures are performed under fluoroscopic guidance. Patients in prone position, under aseptic conditions, 20G curved 100mm RF needles with active tips are placed at the site of the dorsal ramus medial branch of the relevant L3/L4-L5/S1 LFJ’s. Correct placement is confirmed using electrostimulation at 50 HZ for sensory and 2HZ for motor functions. Then 0.5% bupivacaine is injected through cannula to decrease procedure related pain. The RF probe is then reinserted into the cannula and lesioning at a temperature of 80℃ for 90 seconds using RF generator. Then, inj.dexamethasone 4mg is injected to prevent post operative neuritis.