The findings of the study revealed that majority of the subjects (73%) did not have any previous information about computer ergonomics. More than half of the subjects (54%) use computer for 7 and more hours of work. The most common symptoms reported were eye strain (60%), followed by back pain (40%). Of the total, 47% had satisfactory knowledge, 28% good knowledge, 19% poor knowledge, 4% very good knowledge and 2% had very poor knowledge in computer ergonomics. More than half of the subjects (55%) reported partially safe practice, 31% reported mostly safe practice, 14% reported totally unsafe practice and none reported totally safe practice. Also, a weak positive correlation was found between knowledge and self-reported practice of computer ergonomics among the office computer users(r=0.272, p<0.05). A significant association between knowledge of computer ergonomics with gender (p=0.04) and significant association between self-reported practice of computer ergonomics with variables like gender, (p=0.016), hours of work using computer per day (p=0.045), monthly income (p=0.004) and symptoms (p=0.001) was found out. More than half of the subjects strongly agreed that the information booklet was informative (56%) and useful to them (52%).