Rationale: The knee joint is commonly affected in osteoarthritis where the strength of the quadriceps muscle and its torque producing capability is frequently found to be compromised. Recently, the use of kinesio taping as an intervention in musculoskeletal disorders has become popular amongst physiotherapists. However, its ability to improve the isokinetic knee performance has conflicting results in literature with only few studies showing an increase in the quadriceps torque. This warrants further investigation in knee osteoarthritis, forming the basis for this study. Objective: To compare the isokinetic quadriceps torque, standardized stair-climbing task and pain between subjects in experimental and control group before and after kinesio tape application. Materials and method: A double blind pre-test post-test control group design will be followed where 40 subjects will be randomly allocated to either the experimental or control group. Subjects will be recruited from the out-patient departments of orthopaedics and physiotherapy-MS Ramaiah Hospitals using random sampling. The dependent variables for this study are peak quadriceps torque (measured using an isokinetic dynamometer), standardized stair-climbing task (where the time taken to ascend and descend 5 stairs “as quickly and as safely” as possible would be noted) and pain (measured using the visual analogue scale). A pre test measurement of the variables will be carried out by a blinded assessor following which the kinesio tape application will be done by the principal investigator. The blinded assessor will then carry out the post test measurement of the same variables. Statistical method: Descriptive statistics will be used to compare the baseline characteristics of the experimental and the control group (utilizing mean and standard deviation). Student t test (unpaired) will be used to compare the peak quadriceps torque values and the time taken in the standardized stair climbing task between the experimental and control group. The Student t test (paired) will be used to analyze the within group variations for the same. Mann-whitney U test will be used to compare the pain scores of VAS between the experimental and control group with the Wilcoxon signed-rank test used to compare the within group variations.