FULL DETAILS (Read-only)  -> Click Here to Create PDF for Current Dataset of Trial
CTRI Number  CTRI/2021/10/037152 [Registered on: 07/10/2021] Trial Registered Prospectively
Last Modified On: 17/05/2022
Post Graduate Thesis  Yes 
Type of Trial  Observational 
Type of Study   Case Control Study 
Study Design  Other 
Public Title of Study   TO STUDY THE CORRELATION BETWEEN PALMER DERMATOGLYPHIC PATTERNS AND JATYA-ANDH IN CHILDREN WITH SPECIAL REFERENCE TO OCULAR MALFORMATIONS  
Scientific Title of Study   A CASE CONTROL STUDY OF JATYA-ANDH WITH SPECIAL REFERENCE TO ITS RELATION WITH PALMER DERMATOGLYPHICS 
Trial Acronym   
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  TANVI MAHAJAN 
Designation  Ph.D Scholar Department of Rachana Shareera 
Affiliation  Parul Institute of Ayurveda and Research, Parul University 
Address  TANVI MAHAJAN, PhD Scholar, Department of Rachana Shareera, Parul Institute of Ayurveda and Research, PARUL UNIVERSITY, LIMDA, WAGHODIYA VADODARA

Vadodara
GUJARAT
391760
India 
Phone  9569391111  
Fax    
Email  tanu6862@gmail.com  
 
Details of Contact Person
Scientific Query  
Name  Dr BG Kulkarni 
Designation  Professor, Department of Rachana Shareera 
Affiliation  Parul Institute of Ayurveda and Research, Parul University 
Address  Dr. B.G. Kulkarni, Professor, Department of Rachana Shareera, Parul Institute of Ayurveda and Research, PARUL UNIVERSITY, LIMDA, WAGHODIYA VADODARA

Vadodara
GUJARAT
391760
India 
Phone  9480302935  
Fax    
Email  drbgkulkarni@gmail.com  
 
Details of Contact Person
Public Query  
Name  TANVI MAHAJAN 
Designation  Ph.D Scholar Department of Rachana Shareera 
Affiliation  Parul Institute of Ayurveda and Research, Parul University 
Address  TANVI MAHAJAN, PhD Scholar, Department of Rachana Shareera, Parul Institute of Ayurveda and Research, PARUL UNIVERSITY, LIMDA, WAGHODIYA VADODARA

Vadodara
GUJARAT
391760
India 
Phone  9569391111  
Fax    
Email  tanu6862@gmail.com  
 
Source of Monetary or Material Support  
Authoritative Ayurvedic literature like Brihatrayees, Laghutrayees and Books of Hastarekha Shastra (Palmistry) 
Encyclopedias, Dictionaries, Internet sites such as Britannica.com 
Institute for the Blind, Opposite side Lohgarg Gate, Goal Bagh, Amritsar, Punjab-143001 
Modern Medical texts and Related thesis, E-Books 
Peer reviewed journal articles, Academic journals 
 
Primary Sponsor  
Name  Parul Institute of Ayurveda and Research 
Address  PARUL UNIVERSITY, LIMDA, WAGHODIYA VADODARA- 391760, GUJARAT- INDIA 
Type of Sponsor  Research institution and hospital 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Sh Manjeet Singh  Institute for the Blind  Room 7, Institute for the blind, Opposite side Lohgarh Gate, Goal Bagh, Amritsar, Punjab
Amritsar
PUNJAB 		 9017090190

manjitinstitutefortheblind66@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Parul Institute of Ayurveda, Parul University  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition: H540||Blindness, both eyes,  
 
Intervention / Comparator Agent  
snoIntervention/ComparatorTypeDrug-TypeProcedure NameDetails
 
Inclusion Criteria  
Age From  1.00 Day(s)
Age To  16.00 Year(s)
Gender  Both 
Details  Diagnosed patients of jatya-andh between age group of 0-16 years irrespective of sex are selected.
ï‚· Palmer imprints will be taken for dermatoglyphic study. 
 
ExclusionCriteria 
Details  Diseases of hands, Keratosis Palmaris, Impetigo, Palmar psoriasis, leprosy.
Children with Neurological disorder/ Psychiatric illness.
Injuries and scars of hand.
Plantar imprints will be omitted for the study 
 
Method of Generating Random Sequence   Other 
Method of Concealment   Other 
Blinding/Masking   Not Applicable 
Primary Outcome  
Outcome  TimePoints 
Dermatoglyphic alterations may be the result of early prenatal disturbances, so there must be significant difference in the palmer dermatoglyphic patterns of healthy individuals and patients suffering from jatya-andh.  4 weeks 
 
Secondary Outcome  
Outcome  TimePoints 
The purpose of this study is to establish dermatoglyphics a simple and inexpensive means of determining whether a patient had a particular chromosomal defect. The present attempt is to study whether there is a set of pattern of dermatoglyphics in patients with blindness.  4 weeks 
 
Target Sample Size   Total Sample Size="250"
Sample Size from India="250" 
Final Enrollment numbers achieved (Total)= "250"
Final Enrollment numbers achieved (India)="250" 
Phase of Trial   N/A 
Date of First Enrollment (India)   15/10/2021 
Date of Study Completion (India) Date Missing 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Date Missing 
Estimated Duration of Trial   Years="2"
Months="0"
Days="0" 
Recruitment Status of Trial (Global)
Modification(s)  		 Not Applicable 
Recruitment Status of Trial (India)  Completed 
Publication Details
Modification(s)  		 As soon as possible 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary
Modification(s)  
•Research is the quest for new knowledge. The present research is entitled Case control study of Jatya-andh with special reference to its relation with palmer dermatoglyphics.

•Acc to modern science,  genetic factors play a role in many kinds of eye disease, including those diseases that are the leading cause of blindness among infants, children and adults. More than 60 percent of cases of blindness among infants are hereditary such as congenital cataracts, congenital glaucoma, retinal degeneration, optic atrophy and eye malformations.

•According to modern science, eyes and skin, brain all are developed from ectoderm at same time during 10th to 16th week of intrauterine period. If there is any developmental anomaly found in ectoderm, it should be reflected in both of its derivatives, likely to be reflected in the dermatoglyphic patterns.
•Since dermal ridges develop during 6th-13th weeks of gestation, genetic message carried in the genome - normal or abnormal - is deciphered during this period is reflected in dermatoglyphics.

•Dermatoglyphics as a diagnostic aid is now well established in number of diseases which have strong hereditary basis and is employed as a method for screening of different diseases like Cerebral Palsy, Down Syndrome Schizophrenia, Leprosy; Congenital heart diseases, Bronchial asthma and many more has been well documented in recent years.

•The present attempt is to study whether there is a set of pattern of dermatoglyphics in patients with blindness.

* Till date we have collected the palmer dermatoglyphics prints of 250 diagnosed patients of jatya-andh between the age group of 0-16 years and also collected palmer dermatoglyphic prints of 250 normal children of same age group and area.
 
Close