1. What data in particular will be shared?
   Response - Individual participant data that underlie the results reported in this article, after de-identification (text, tables, figures, and appendices).
   


2. What additional supporting information will be shared?
   Response -  Study Protocol
   Response -  Statistical Analysis Plan
   Response - Informed Consent Form
   
   
3. Who will be able to view these files?
   Response - Researchers whose proposed use of the data has been approved by an independent review committee identified for this purpose.
   


4. For what types of analyses will this data be available?
   Response - For individual participant data meta-analysis.
   


5. By what mechanism will data be made available?
   Response (Others) -  On personal request through mail at drmsadik@gmail.com


6. For how long will this data be available start date provided 07-04-2023 and end date provided 31-03-2028?
   Response - Beginning 9 months and ending 36 months following article publication.
   


7. Any URL or additional information regarding plan/policy for sharing IPD? 
   Additional Information - NIL

Pre-anaesthetic evaluation will be done for all the patients, a day before surgery. All patients will be thoroughly explained about the procedure. They will also be made well conversant about the Numeric Rating Scale (NRS) ranged from 0 to 10 (0 = no pain and 10 = worst imaginable pain). The standard instruction of fasting will be given to all patients (2 hours for clear liquids and 6 hours for semisolid and solid food).

On arrival of the patient in preoperative holding area, patient identification, fasting status, consent, and PAC will be confirmed. In the procedure room, standard ASA monitors like electrocardiogram (ECG), non-invasive blood pressure (NIBP) pulse oximetry will be attached and baseline vitals will be recorded. A peripheral intravenous cannula will be secured in ipsilateral upper limb and intravenous fluids will be started. All patients will receive combined spinal epidural (CSE). Epidural space will be identified using loss of resistance to saline subarachnoid block will be performed using needle through needle technique with bupivacaine 0.5% heavy 15 mg. Epidural catheter will be secured and a test dose (3 mL of lignocaine 1.5% with 5 mcg/mL epinephrine) will be administered through the catheter. Following CSE, one of the intervention techniques as per randomization will be performed.

Following the block patients will undergo the scheduled surgery. During the surgery vitals [heart rate (HR), mean arterial pressure (MAP), oxygen saturation (SpO₂) and temperature] will be recorded. No further analgesics will be administered during the surgery. After completion of surgical procedure, patients will be shifted to PACU.

Postoperative analgesia will be assessed using NRS immediately after receiving the patient in the PACU and thereafter at 1-hour, 3-hours, 6-hours, 12-hours, 18-hours and at 24-hours. On recording of NRS ≥4 or on patient demand rescue analgesia (10 mL 0.2% ropivacaine) through epidural catheter will be administered and time to rescue analgesia will be recorded. Total epidural boluses during the observation period will also be recorded.

The motor blockade will be assessed at predefined time interval by testing the quadriceps motor function with the patient supine and with the hip and knee flexed at 45º and 90º, respectively. The patient will be asked to extend the knee first against gravity and then against resistance. Quadriceps strength will be graded according to a 3-point scale: normal strength = 0 point (extension against resistance); paresis = 1 point (extension against gravity but not against resistance); and paralysis = 2 points (no extension).

Patient satisfaction will be recorded on a four-point Likert’s scale as 1- excellent; 2- good; 3- fair and 4- poor.

Block performance time defined as time interval between putting the ultrasound probe and completion of LA agent.

Periprocedural complication like vascular puncture, paresthesia, systemic LA toxicity etc will be recorded.