Prameha is a disease well known since Vedic period. It is one of the Ashta mahagada¹ and also considered as Agrya among Anushangi vikaras² .Prameha has been described as chirakalina vyadhi in which Tridosha vriddhi with special involvement of kapha and kleda are seen, with the cardinal feature of Prabhutha avila mutrata³ .The further progression of Prameha may affect all the 10 Dushyas and leads to upadrava⁴.

Type 2 Diabetes mellitus can be correlated to prameha in Ayurveda classics, which is characterized by reduced sensitivity to the action of Insulin and inability to produce sufficient insulin to overcome the insulin resistance.⁵ It is the most common type of diabetes worldwide, and develops commonly in people above 40 years. Worryingly, complications are usually common in individuals with Type 2 Diabetes mellitus ,when it’s left untreated in the early stages.

According to current statistics Diabetes mellitus affects about 69.1 million Indians which comprises 8.9% of the Indian adult populations⁶. Type 2 diabetes accounts for about 4.6 million deaths worldwide every year and is projected by WHO to be the 7^th leading causes of death by 2030⁷.So, this is an alarming situation demanding an effective management in Type 2 Diabetes mellitus.

 Though many research works are conducted on prameha, scientists are struggling to search an effective and harmless remedy. It has always been treated by oral hypoglycemic agents and insulin, but they all have adverse effects and unaffordable as well. Therefore, from the patients perceptive, minimizing the burden imposed by type 2 Diabetes mellitus requires an approach that ensures service which is accessible and affordable.

kataka beeja (seed of strychnos  potatorum Linn.) is one of the drug which is easily available and affordable, having Kapha medhohara property, and it is specifically indicated in Prameha with Takra as Anupana⁸

The ease of use, safety and multiple health benefits of yoga have led to be more widely accepted by the society and considered as low cost intervention to control lifestyle disorders includes Diabetes. Recent Studies shows that Performing the specific yogaasanas explained in Prameha result in the regeneration of pancreatic cells and helps to improve the sensitivity of Beta cells to glucose thereby improving the insulin secretion  .While pranayamas  indicated for Prameha are useful in slowdown the mind, thereby reduces stress  level and helps to lower blood sugar levels⁹.

The current study aims to explore a new, safe, effective and cheaper management base for Type 2 Diabetes mellitus and this would be significally address burning issues of Diabetes in society.

In this regard, to evaluate the individual & comparative efficacy of katakabeeja churna with takra as Anupana & yogic techniques in the management of Prameha (Type 2 Diabetes mellitus) is undertaken for study.