Introduction: Oral lichen planus[ OLP] is a chronic inflammatory mucocutaneous disease characterized by outbreaks or flares.¹ It affects 0.2-1.9%of the population.^2,3Although etiology is unknown, pathogenesis of oral lichenplanus is known to involve an immune disorder,with epithelial damage caused by cytotoxic CD8+lymphocytes^1,2,3,4.The disease can produce considerable morbidity and alter patient quality of life,particularly in the presence of ulcerative lesions^4,5. A variety of treatments have been proposed for Oral lichen planus:topical or systemic corticosteroids,cyclosporine,retinoids,azathioprine,tacrolimus, pimecrolimus,photochemotherapy and surgery^4,5.The main inconvenience of these treatments is represented by the sideeffects they usually produce.^3,4 Aloe vera(AV) (Aloe barbadensis miller) is a member of the liliaceae family⁶ It is widely used as a natural  alternative therapy for various types of diseases, and several studies have suggested the healing ,cosmetic & nutritional benefits of this plant^{6 .}Aloe vera  exerts anti-inflammatory effects through the reduction of leucocyte adhesion &TNF- levels^7,8,9  and the effect of topical aloe vera in Oral lichen planus has been studied and reported by Hayes ¹⁰ and Choonhakarn et al.¹¹

Objectives: To observe the efficacy of topical aloe vera in oral lichen planus by,

                   1)  assessing the reduction in size of the lesion by clinical examination

                   2)assessing  the reduction in burning sensation  using visual analog scale   

Materials and Methods: Patients who are diagnosed clinically and histopathologically as having  oral lichen planus will be treated with topical aloe vera .Duration  of  this  study  will be  approximately  1 yr from (june 2012- june 2013) Aloe vera gel will be used here which contains about  70% concentration of  aloe vera .It  is mainly the leaf pulp of  this  plant.Instructions should be given to relieve  stress  by patient councelling & reassuarance  after informed consent.Biopsy will be done under local anesthesia in patients who are clinically diagnosed as having Oral Lichen planus in Department of Oral Medicine & Radiology .Pre treatment photographs will be taken  as well as size of the lesion will  be measured every week.Biopsy specimen will be send to the Department of Oral pathology  & Microbiology  for histopathological investigations.After confirming the diagnosis,  treatment  of Oral lichen planus will be carried out  in Oral Medicine department  by topical  aloe vera preparation .Aloe vera gel of 70% concentration will be used [ from Hiran Agroceuticals Pvt Ltd, Madurai, India ].Duration of study/treatment is approximately 1yr.Method  of  application  is topical by using a gauze spatula thrice daily  for 12 weeks.It is allowed to remain in the mouth for 1 minute.After 1minute  patient is asked to swish & spit.Patients will be reviewed  on a weekly basis.On every recall visits  size of lesion will be measured clinically which will be well supported by pre & post treatment photographs .Degree of  burning sensation will be measured  using the Visual analog scale.