Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Chronic pain is that pain which persists at the surgical site and nearby surrounding tissues 3 months after surgery. Despite adequate research chronic postoperative pain continues to be a significant problem in hernioplasty. Polyester mesh has a higher degree of connective tissue integration, it has less mesh contraction, less fibrous encapsulation and less stiffness around the mesh. Prosthetic materials induce an inflammatory response characterized by an increased level of IL-6 and hsCRP, however, there is no significant difference between preoperative

level, 12 hr, 48hr, and 2weeks. The main reasons hypothesized for chronic groin pain are per-operative nerve damage, post-operative fibrosis, or mesh-related fibrosis. They have been classified as either neuropathic or non-neuropathic pain. The three nerves potentially involved are the Ilioinguinal Nerve (IIN), Iliohypogastric Nerve (IHN) and genital branch of the Genitofemoral Nerve (GFN). These nerves can be damaged either by trauma during dissection or retraction of tissues, or nerve entrapment from post-operative fibrosis, mesh-related fibrosis or sutures used to fix the mesh. Non-neuropathic causes are excessive scar formation resulting from prosthetic mesh reaction, the periosteal reaction from sutures or staples inserted into the pubic tubercle or due to rolled-up bulky mesh leading to mechanical pressure. Hereby we are conducting a study to compare the efficacy between polypropylene mesh and polyester mesh in terms of pain, inflammatory changes