The successful outcome of endodontic treatment depends on through disinfection. Based on this concept, the ultimate goal of endodontic therapy is to eliminate or remarkably minimize the microbes and their toxic products from the root canal before obturation.

However the complex morphology of root canal system, invasion of microbes into the dentinal tubules, and formation of smear layer during instrumentation are the major obstacles in achieving complete cleaning and shaping of the root canals.The role of mechanical instrumentation alone in removing microbes from the root canals has been investigated in many studies, and majority of them have found a significant reduction in the microbial count with an increasing preparation size and irrigation However, Peter and Wesselink found that more than 35% of root canal walls remained untouched even by modern rotary Ni‑Ti instrumentation techniques.

Sodium hypochlorite is the gold standard and the most effective irrigating solution but owing to the potential side effects, constant increase in antibiotic strains, safety concerns and cytotoxic reactions there is a need for an alternative.

Calcium hypochlorite is antimicrobial, relatively more stable, higher available chlorine ion percentage and induces minimal inflammatory response when compared to Sodium hypochlorite.

Due to increased cytotoxic reactions of synthetic irrigants, usage of various herbal agents has increased over the last few decades.