INTRODUCTION
BMD refers to Bone Mineral Density, a measure of bone density, reflecting the strength of bones. It detects osteopenia (mild bone loss) and osteoporosis (more severe bone loss) when performed. It measures bone density or mass compared to a healthy person of the same age and gender. BMD measurements, known as T-scores, determine bone density and reveal whether it is normal, osteopenia (low bone mineral density), or osteoporosis (more severe low bone mineral density).
Low bone mass that isn’t precisely osteoporosis is referred to as osteopenia. It is a condition in which bone mineral density is lower than average. It’s thought to be a precursor to osteoporosis. Osteoporosis is a widespread clinical condition affecting multiple bones in which bone tissue density is reduced quantitatively, resulting in a brittle skeleton.
Osteopenia, often known as low bone mass or low bone mineral density, is an ailment in which the bone mineral density is low. Due to the bone being weaker, it can increase the likelihood of fracture and may lead to osteoporosis later in life.
Osteoporosis is a worldwide public health concern wherein the number of people with osteoporosis and fractures is expected to increase as the number of elderly people in developed and developing countries grows. Strong bones are essential for our health since they play a vital part in the body’s overall function. Moreover, as they provide a frame for the body and protect vital organs such as the heart and other organs, they also offer support and structure.
Ayurveda is one of the most ancient medical sciences in the world. It conceives and describes the basis & applied aspect of life process, health, disease & its management in terms of its principles & approaches. There is no exact clinical entity mentioned in Ayurvedic classics like low bone mineral density or osteoporosis; however, the bone conditions Asthi-Kshaya and Asthi Saushirya have some clinical resemblance. Asthi-Saushirya is mentioned as a Majja-Kshaya, whereas; Asthi-Kshaya is cited as an independent condition. Asthi-Kshaya is ‘decrease in the bone tissue’ and Asthi-Saushirya means’ porous bones.’ Hemadri has commented on the word ‘Saushirya’ as ‘Sarandhratvam,’ which means ‘with pores.’ This condition is explained in the context of Majja-Kshaya. Asthi, considered as the major seat of Vayu and the condition of Asthi-Majja-Kshaya can lead to aggravated Vata Dosha.
Acharya Charaka has advocated the use of Snehana for aggravated Vata in Asthi and Majja Dhatu. He has indicated Basti as the Ardhachikitsa for the Vataj disorders and in Asthi-Kshaya. Aggravated Vata Dosha is responsible for the pathogenesis of Asthi-Majja-Kshaya. Considering osteopenia and osteoporosis as a degenerative Vata dominant bone disorder, the present clinical study was planned to evaluate the efficacy of Matra Basti and Shaman Chikitsa mentioned in the treatment of Vatavyadhi. For Matra Basti, two oil-based formulations, viz: Vrishyamuladi Taila and Shatavari Taila, were selected for evaluating the comparative efficacy, whereas, for Shaman, Vyoshadhya Gutika Guggulu was selected as indicated in the treatment of Asthi-Majja-Kshaya.
WORK PLAN
GROUPING: Subjects were randomly divided into two groups:
Group A: 17 Patients in this group were given Vrishyamuladi Taila Matra Basti and Vyoshadhya Gutika Guggulu
Group B: 17 Patients in this group were given Shatavari Taila Matra Basti and Vyoshadhya Gutika Guggulu.
ASSESSMENT: On the basis of BMD score and Ayurvedic Parameters, assessment was done before treatment, after treatment and during last follow up.
PROCEDURE:
Group A: Patients in this group were given Vrishyamuladi Taila Matra Basti and Vyoshadhya Gutika Guggulu
a. Sthanik Abhyang and Swedan was done for 16 days during the morning period, before administering Basti.
b. Vrishyamuladi Taila Matra Basti, in the dose of 60 ml, once daily was administered through rectal route as per “Kala Basti†schedule, for 16 days.
c. Vyoshadhya Gutika Guggulu was administered in the dose of 1g twice a day orally with lukewarm water for 30 days, after Basti was completed.
Group B: Patients in this group were given Shatavari Taila Matra Basti and Vyoshadhya Gutika Guggulu.
a. Sthanik Abhyang and Swedan was done for 16 days during the morning period, before administering Basti.
b. Shatavari Taila Matra Basti, in the dose of 60ml, once daily was administered through rectal route as per “Kala Basti†schedule, for 16 days.
c. Vyoshadhya Gutika Guggulu was administered in the dose of 1g twice a day orally with lukewarm water for 30 days, after Basti was completed.
Effect of Therapy on Subjective Parameters in Group A:
There was a 41.94% improvement reported in Asthishoola (bone pain), followed by 54.17% improvement in Asthitoda (pricking pain in bone), 50.00% improvement was noted in Nakhabhanga (splitting of nails), 42.86% improvement was noted in Raukshya (dryness), 47.62% improvement was noted in Aswapna (loss of sleep), 52.63% improvement was noted in Satataruka (continuous pain).
Effect of Therapy on Subjective Parameters in Group B:
There was a 52.78% improvement reported in Asthishoola (bone pain), followed by 46.88% improvement in Asthitoda (pricking pain in bone), 54.55% improvement was noted in Nakhabhanga (splitting of nails), 50.00% improvement was noted in Raukshya (dryness), 46.43% improvement was noted in Aswapna (loss of sleep), 39.29% improvement was noted in Satataruka (continuous pain).
Effect of Therapy on Objective Parameters in Group A:
There was a 4.69% improvement observed in Vitamin D3, then 1.06% improvement was observed in Serum Calcium and 1.49% improvement was observed in BMD levels.
Effect of Therapy on Objective Parameters in Group B:
There was a 4.43% improvement observed in Vitamin D3, then 1.16% improvement was observed in Serum Calcium and 1.87% improvement was observed in BMD levels.
Comparison of Objective Parameters between Group A and Group B
It was observed that there is no significant difference in any of the parameters tested in both the Group A and Group B comparisons.
Conclusion
Ø It is concluded that there is no difference between the effect of Vrishyamuladi Taila Matra Basti and Shatavari Taila Matra Basti followed by Vyoshadhya Gutika Guggulu in the Management of Asthi-Majja-Kshaya (Low Bone Mineral Density).