Pain is the most common symptom that brings patients to see a physician and it is the basic and most challenging problem for surgeons from primitive era and is the very common post-operative manifestation after any surgical procedure, no matter how good operation is performed. Excessive pain will be unbearable and will lead to other effects like nausea, palpitation and increase or decrease of blood pressure. When post-operative pain is inadequately treated the suffering of the patient increases the stress of the whole procedure and can delay recovery.

Hence management of postoperative pain has been a global challenge since the inception of surgery with opiates especially, there are exaggerated fears regarding their potential for side effects and their addictions. In present modern era also a well-established NSAID, Diclofenac sodium has various side effects like nausea/vomiting, ulceration, GI bleeding and adverse renal effectsi.

Acharya Sushruta has explained specifically in Sutrastana about the management of pain in post-operative condition. He has mentioned that in the pain which is caused post- surgery, can be manage by the application of yashtimadhu and luke warm ghrita and this formulation has been proved to be effective.

The lack of effective analgesics in Ayurvedic medicines is the main disadvantage for the down fall of Ayurvedic surgery, so there is constant quest for an ideal Ayurvedic analgesic therapy. There is immense amount of pain in the post-operative conditions, due to which patients are afraid to undergo surgery. So, in order to overcome this problem and to create a new treatment modality in Ayurveda for pain management an attempt is made by preparing suppositories using Yastimadhu, which is easily available, cost effective and easy to prepare.