Sthaulya is mentioned among santarpanajanita vyadhi in Ayurvedic texts. In Sthaulya etiological factors mainly vitiate meda-kapha and vata get avarita by excessive Meda. Thus if we use only aptarpaka dravya, it increases the vitiated vata. Therefore, treatment should be planned considering vitiated vata, meda and kapha. Panchakarma is the prime tool of Ayurvedic therapies, mainly considered as shodhana therapy. Acharya Charaka quoted that there is a chance of recurrence of disease treated by Shamana therapy but Shodhana therapy cures the disease from its root and there is no chance of recurrence.

Lekhana basti  is mentioned by different ayurvedic texts, for the treatment of Santarpanotha Vyadhi, Kaphaja Roga and Kaphavrita Vata. The word ‘Lekhana’ itself indicates its action that is "Lekhanam Patlikaranam" - scarifying helps in reduction of fat. Sharangadhara considered Lekhana in a wide sense as Deha Visoshanam, ‘Dhatun - Malan va Dehsya Vishoshya Lekhayechha yat Lekhanam i.e. the process of drying up or desiccation of all excess Dosha, Dhatu and Mala. Basti denotes karma in which the drugs are administered through the anal canal and it stays for a certain period of time and then they draw the waste substances from all over the body in to the colon and eliminate them out of the body by producing movements in the colon resulting in to the pleasant effect.

 Shodana in the form of Basti karma is mentioned as unique treatment modality in Sthaulya specially with the drugs which are of ushna, tikshna, Lekhana that help in combating Kapha and medodushti. Lekhana Basti is emphasized by all the authors of Ayurveda as treatment procedure in Medoroga. Considering this aspect, Lekhana is opted for this study. Lekhana basti will be prepared in the same format of Asthapana Basti.

 Trayushnadya loha is a popularly used oral medicine, mentioned in Yogaratnakara as shamanoushadhi for Medoroga Chikitsa. The ideal shamana in the treatment of Sthaulya is usage of Vata, kaphahara, and Medohara properties. Oral administration of various drugs like Shilajatu, Triphala, Guggulu Prayoga, Madhvambu Prayoga, Gomutra Prayoga etc has been indicated. In the treatment of Sthaulya, the drug administration for the purpose of Karshana, should be Pragbhakta (before meal). Hence Trayushnadya Loha the drug is with a combination of Aamalaki, Vibheetaki, Hareetaki, Shunti, Pippali, Maricha, Chavya, Chitraka, Bakuchi, Bida lavana, Audbhida lavana, Saindhava lavana and Souvarchala lavana with equal amount of Loha bhasma, that  have ushna virya and laghu, ruksha guna and are exactly opposite to the gunas of kapha and medodhatu,  is planned to evaluate its therapeutic efficacy in sthaulya.

In spite of vigorous research works on this area with different modalities of the treatment, mankind is still leading miserable life with this disease. It is the need of the hour to explore an effective, economic, domiciliary management for this disorder. Ayurveda emphasizes various treatment modalities in the treatment of Sthaulya roga that includes both Shodhana and Shamana which are of Rukshana and Apatarpana in nature.  Thus considering gravity of the problem and availability of effective remedy this study entitled A COMPARATIVE CLINICAL TRIAL EVALUATING theTHERAPEUTIC effECT of LEKHANA BASTI AND TRAYUSHNADYA LOHA in  sthaulya w.s.r. TO OBESITY is planned to evaluate and to compare the efficacy of Lekhana Basti and Trayushnadya Loha in Sthaulya.