Nasya Karma, one among Panchakrama is a process by which medicated oil is administered through the nostrils to alleviate diseases of jatrurdwa.

The sedentary lifestyle and stress filled modern era has led to alterations in the activities of neuro-endocrine systems causing newer health challenges like hypothyroidism. Hypothyroidism, occurs when the thyroid gland does not produce enough thyroid hormones. It is continued to be posing a major health challenge in both developing and developed world. There is 4.5% prevalence of Hypothyroidism in developed world. The prevalence of subclinical hypothyroidism in developed world is 4-15%. The prevalence of hypothyroidism in urban India is 10.95%. Major portion of Hypothyroidism remain undetected. Incidence of Hypothyroidism is more in females (7:1) and elderly people¹. Management of Hypothyroidism with the modern drugs may bring the value of TSH and T4 to normal range, but increased dosage and continuous medication make the patient drug dependent till the end of mortal life. So a better and safer therapy is needed for the patient society through the heritage of Ayurveda. Hence an effort is made to treat hypothyroidism in a safer and effective way.

The thyroid disorders can be studied under Galaganda. Involvement of Kapha is invariable associated with Kupita vata and dusta Medas^2a. The stana of thyroid gland being jatrurdwa and being a kapha stana, Marsha Nasya is selected for its shodana action.Previously a work on Katutumbi taila Nasya with katu taila^3a base was done, which had very good results. However Subjects had irritation in nose due to its atiteekshna guna, hence in order to reduce its teekshnata, Katutumbi taila with tila taila^4a as the base is used in present study. This is compared to Himsradi taila^4b Nasya which also has usna and teekshna guna, thus the desired shodana effect is achieved.