Periodontal diseases are among the most common infections disturbing human kind and can lead to the demolition of the periodontal ligament, cementum, gingiva, and alveolar bone. Plaque is the primary etiological factor in gingival inflammation. The progression of the disease is by microbial biofilm formation(dental plaque) which leads to periodontal inflammation and then attachment loss as well as alveolar bone loss.¹

                   Despite the advances in various field of medicine, oral infections and dental caries are still considered as serious public health problems and inflict a major burden to health care services around the world and especially in developing countries. Development of resistance against antibiotics and antiseptics is a growing cause of concern which has limited the preventive measures. Therefore, there is a continuing need to search for new antimicrobial agents. Over the last decade, plant antimicrobial activity has been studied in different region of the world.²

                Licorice root [Glycyrrhiza glabra Linn] is an ancient herb that had been used as a traditional medicine and sweetener in various parts of the world for over 4,000 years. It belongs to the pea family (Leguminosae) which includes 30 species, along which G. glabra & G. uralensis is widely used as antibacterial and anti-inflammatory agents. The roots and rhizomes of the licorice are used. Licorice has anti-inflammatory, antiviral, antibacterial, antispasmodic, antioxidative,  antiallergic,  hepatoprotective,  expectorant activities.³

                          As there are no studies regarding Licorice extract as a local drug delivery, thus this study aim to assess the efficacy of  Licorice root extract as local drug delivery as an adjunct to scaling and root planing in treatment of chronic periodontitis.