Mutrakrichchra is a disease of mootravaha strotas the term Mutrakrichchra comprise of two words -Mutra and Krichra.The term Mutram is derived from the root Muta+Ghanzh prtayaya which means Mutra prasravane i.e ooze.The term Krichchra is derived from the root Krish-Kaste means causing trouble or painful.The disease in which urine is passed with difficulty is called Mutrakrichchra .Considering it can be inferred that Mutrakrichchra is a condition of urogenital system with dysuria as prime symptom which includes UTI.[i]

 Urinary tract infections is an infection that affects parts of urinary tract when it affects the lower urinary tract.UTI are caused by bacterium Escheichia coli,[ii]cause 80% of acute infections in patients withouts urologic abnormalities or calculi Other gram negative rods,especially proteys and Kleibseella and occasionally Enterobacter,account for a smaller proportion of uncomplicated infections some lifestyle disorders like poor personal hygiene, having a urinary catheter,bowel incontinence,kidney stone,some forms of contraception’s .UTI is the most common bacterial infections managed in general medical practice and account for 2-5% of consultations ,upto 50%of women have a UTI at some time .The prevalance of UTI in women is  about 3% at the age of 20 ,increasing by about 1% in each subsequent decade.[iii]

Cystitis and urethritis the two forms of lower urinary tract infections (LUTI) are nearly 10 times more common in males than females, mainly in reproductive age. Bacterial presence places the entire urinary system at risk of invasion. Dysuria is one among the important symptoms of lower UTI by which the patients, daily activities are hampred. Patient with cystitis and urethritis may be asymptomatic or present with frequency,urgency,supra pubic pain and dysuria .[iv]

These conditions of lower UTI has similar symptoms of mootrakrichra like muhurmootra pravrutti,sadaaha mootrapravrutti,saruja mootrapravrutti. In Ayurveda there are so many formulations mentioned for the mootrakrichra, even though number of researches have been carried out still there is need of an effective and safe formulation for this disease. [v]

The method of management of UTI are mainly by antibiotics. Even though they are useful they involve considerable amount of risk and are also expensive at the same time the infective organism develops resistance to antibiotics.So there is need of safe palatable, cost effective medicine.

The trikantakadya guggula from yogaratnakara contains gokshur guggul, haritaki, bhibitaki, amalki , nagarmotha.Each and every ingredient is having mootra krichra property. For that an attempt has been taken for research work to see the efficacy of trikantakadya guggulu[vi]