1. What data in particular will be shared?
   Response - Individual participant data that underlie the results reported in this article, after de-identification (text, tables, figures, and appendices).
   


2. What additional supporting information will be shared?
   Response -  Study Protocol
   Response -  Statistical Analysis Plan
   Response - Informed Consent Form
   
   
3. Who will be able to view these files?
   Response - Researchers whose proposed use of the data has been approved by an independent review committee identified for this purpose.
   


4. For what types of analyses will this data be available?
   Response - For individual participant data meta-analysis.
   


5. By what mechanism will data be made available?
   Response (Others) -  By personal request through mail at drmsadik@gmail.com


6. For how long will this data be available start date provided 04-07-2021 and end date provided 04-04-2026?
   Response - Beginning 9 months and ending 36 months following article publication.
   


7. Any URL or additional information regarding plan/policy for sharing IPD? 
   Additional Information - NIL

Background: Perioperative pulmonary aspiration risk increases with increased preoperative gastric volume; hence traditionally, patients are kept fasted overnight before surgery. Current guidelines recommend 2-hours clear fluids fasting prior to anaesthesia. However, emerging evidence favours allowing 3 mL/kg clear fluids up to 1-hour before anaesthesia. We compared the gastric volume and gastric emptying time after ingestion of 3 mL/kg and 5 mL/kg of clear fluids.

Methods: Forty-four children were enrolled after getting informed and written consent from parents. On the day of surgery, baseline gastric volume was estimated using ultrasound and patients were randomly allocated in to two groups of equal number i.e. Group 3 and Group 5 (patients received 3 mL/kg and 5 mL/kg 5% Dextrose respectively). Repeated gastric ultrasound was done at every five-minutes interval until the gastric volume reached at baseline. The primary objective of the study was to compare gastric volume and gastric emptying time while secondary objectives were occurrence of PONV, occurrence of irritability and parent’s satisfaction.

Results: The demographic profile, preoperative fasting duration and baseline gastric volume was comparable between groups. In both groups, compared to baseline the gastric volume increased significantly following fluid ingestion and then decreased exponentially to reach at baseline within 1-hour. The median (IQR) gastric emptying time and emptying t_1/2 (minutes) in group 3 was 35.0 (28.75, 40.0) and 17.00 (15.73, 21.50) respectively while in group 5 it was 40.0 (28.75, 45.0) and 18.55 (15.98, 21.98) respectively (p=0.16 and p=0.44 respectively).  The occurrence of nausea, vomiting and irritability as well as parent satisfaction were comparable between the groups (p>0.05).

Conclusion: As the gastric volume returned to baseline within 1-hour even after ingesting 5 mL/kg clear fluids, the preoperative fasting time can be reduced to 1-hour and children can be safely allowed to drink up to 5 mL/kg clear fluids.