Pulpectomy is indicated in teeth that show evidence of chronic inflammation or necrosis in the radicular pulp, with or without periapical or furcation pathology. However, endodontic treatment of primary teeth is more challenging than that of their permanent counterparts; this is because of their anatomical complexities of their root canal systems and their proximity to the developing permanent tooth, coupled with the difficulty in behavior management in children. Presently, the most commonly used materials are: Zinc-Oxide Eugenol, Iodoform based pastes, and calcium hydroxide.  In 1967, it was shown that ZOE set in a dense mass which resisted resorption and was very irritating to the periapical tissues in rats.  In 1979, it was speculated that the resorption rate of ZOE and the root differed, resulting in small areas of ZOE paste possibly being retained and because of its hardness it might deflect the path of eruption of the succedaneous tooth.  It also has limited antibacterial action, and cause necrosis of bone and cementum.  Dominguez et al, reported that combining Iodoform and Calcium Hydroxide, it gave a success rate of 100%.  But the main disadvantage was intra-radicular resorption of the material.  A mixture of Calcium Hydroxide, ZOE, and Iodoform [ENDOFLAS] gave a success rate of 83% with good healing, having the resorption limited to the excess extruded extraradicularly, without washing intra-radicularly and resorptive capabilities and was said to be a good alternative to the traditionally used materials.  There have been only limited human studies on this subject. The present study aims to evaluate the clinical and radiographic efficiency of three root filling materials – ZOE with Iodoform [RC Fill], Calcium hydroxide with Iodoform [VITAPEX], ZOE and Calcium hydroxide with Iodoform [ENDOFLAS], for a period of 3,6 and 12 months.