The Vruna is one which causes gatravichurnana and does the vivarnata of the shareera which is described as a break in the continuity of tissue, from violence or trauma and is regarded as healed if there is a restoration of the wounded or inflamed tissue to normal condition. Wound healing is an important biological process involving tissue repair and regeneration and various stages. Worldwide prevalence of wounds is 1%, estimated that 1.5 million cases of traumatic wounds found every year, whereas an Indian perspective of hospital based study shows diabetes (23%), venous disease (11%) and trauma (13%), and were the important causes of extremity wounds. We get the reference of Vruna description in detail in regards to definition, classification and management in the classics. Its effective management for a surgeon is the basic skill required on which the outcome of surgery revolves. There was, however, a hundred percent (100 %) healing in the animals treated with ointments containing 100mg/g of Haridra(Curcuma longa), and Durva (Cynodon dactylon) in cationic emulsifying agent after treatment, as the wound sizes reduced to zero. Many herbal preparations have been tried in the past research studies as vruna ropana but they had their own drawbacks like they have time consuming. So keeping this as main goal the present study is under taken to evaluate the efficacy of Durvanisha ointment in clinical trial.