Suppositories are one such dosage form that can be used in post-operative pain especially in anorectal surgeries. Sodium diclofenac is of NSAID category which has been shown to have analgesic effects in various conditions.

Though diclofenac rectal suppository is widely used they are associated with high risk factors and warnings like headache, dizziness, light headedness, drowsiness, loss of appetite, local rectal irritation, ringing in the ears, vision loss, rectal bleeding. Other serious side effects like black stools, persistent stomach pain, vomit that looks like coffee grounds could develop. Allergic reactions like rashes, itching, swelling, trouble breathing could also develop as an adverse effect of diclofenac suppository.⁵

According to Ayurveda, parikartika is a vyadhi caused by vata and pitta dosha and anuvasana basti is treatment explained. But this involves a lot of exercise.The patient should be advised with pathya and apathya of both ahara and vihara, the basti dravya must be warmed priorly before instillation, care should be taken to avoid basti vyapaths and the patient will always need the assistance of his doctor for treatment. Most of these problems can be avoided by using an appropriate dravya(vata pitta hara, shoola hara) converted to a suppository form by being molded with a snigdha dravya which still satisfies the definition of basti(vas nivase) by staying in the rectum for a stipulated period of time and facilitating slower drug release to provide a better action.

To prevent all these problems and to prevent the adverse effects of allopathic drugs the present study is planned to evolve an effective treatment by ayurvedic approach in post-operative pain management. In this study an attempt is made to evaluate the efficacy of Gandhaka Rasayana rectal suppository which is tridosha shamaka, vatamaya nivaraka agnivardhaka, rasayana and most importantly shoola hara.