FULL DETAILS (Read-only)  -> Click Here to Create PDF for Current Dataset of Trial
CTRI Number  CTRI/2018/07/014735 [Registered on: 04/07/2018] Trial Registered Prospectively
Last Modified On: 03/07/2018
Post Graduate Thesis  No 
Type of Trial  Observational 
Type of Study   observing about knowledge and practice of low flow anaesthesia 
Study Design  Other 
Public Title of Study   low flow anaesthesia practice and knowledge in Indian government teaching hospital 
Scientific Title of Study   Knowledge and practice of low flow anaesthesia: A survey and observational study of low flow anesthesia 
Trial Acronym   
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Shyam Charan Meena 
Designation  Assistant Professor 
Affiliation  PGIMER, Chandigarh 
Address  DEPARTMENT OF ANAESTHEHSIA & INTENSIVE CARE, 4TH FLOOR, MAIN OT COMPLEX, NEHRU HOSPITAL, PGIMER, SECTOR 12, CHANDIGARH

Chandigarh
CHANDIGARH
160012
India 
Phone  7891669817  
Fax    
Email  drshyam.pgi@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  Shyam Charan Meena 
Designation  Assistant Professor 
Affiliation  PGIMER, Chandigarh 
Address  DEPARTMENT OF ANAESTHEHSIA & INTENSIVE CARE, 4TH FLOOR, MAIN OT COMPLEX, NEHRU HOSPITAL, PGIMER, SECTOR 12, CHANDIGARH


CHANDIGARH
160012
India 
Phone  7891669817  
Fax    
Email  drshyam.pgi@gmail.com  
 
Details of Contact Person
Public Query
 
Name  Shyam Charan Meena 
Designation  Assistant Professor 
Affiliation  PGIMER, Chandigarh 
Address  DEPARTMENT OF ANAESTHEHSIA & INTENSIVE CARE, 4TH FLOOR, MAIN OT COMPLEX, NEHRU HOSPITAL, PGIMER, SECTOR 12, CHANDIGARH


CHANDIGARH
160012
India 
Phone  7891669817  
Fax    
Email  drshyam.pgi@gmail.com  
 
Source of Monetary or Material Support  
primer Chandigarh 
 
Primary Sponsor  
Name  PGIMER CHANDIGARH 
Address  DEPARTMENT OF ANAESTHESIA , 4TH FLOOR, MAIN OT COMPLEX, NEHRU HOSPITAL, PGIMER, SECTOR 12, CHANDIAGRH 
Type of Sponsor  Research institution and hospital 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
SHYAM CHARAN MEENA  4th floor elective operation complex ot   DEPARTMENT OF ANAESTHEHSIA, 4TH FLOOR, MAIN OT COMPLEX, paediatric OT, Eye OT
Chandigarh
CHANDIGARH 
7891669817

drshyam.pgi@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Institutional Ethics Committee Postgraduate Institute of Medical Education and Research  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Healthy Human Volunteers  knowledge and practice of low flow anaesthesia among anaesthesia providers like anaesthesia residents. 
 
Intervention / Comparator Agent  
Type  Name  Details 
Comparator Agent  not applicable  not applicable 
 
Inclusion Criteria  
Age From  20.00 Year(s)
Age To  40.00 Year(s)
Gender  Both 
Details  all residents will be asked for their knowledge and practice attitude about low flow anaesthesia 
 
ExclusionCriteria 
Details  participant refusal considered as exclusion criteria 
 
Method of Generating Random Sequence   Not Applicable 
Method of Concealment   Not Applicable 
Blinding/Masking   Participant Blinded 
Primary Outcome  
Outcome  TimePoints 
to know about knowledge and practice of low flow anaesthesia in tertiary care centre  AT WORKING OT TIME THAT INCLUDES MORNING 8 AM TO 4 PM, 
 
Secondary Outcome  
Outcome  TimePoints 
not available  6 months  
 
Target Sample Size   Total Sample Size="60"
Sample Size from India="60" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   16/07/2018 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="0"
Months="6"
Days="0" 
Recruitment Status of Trial (Global)   Not Applicable 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   NONE YET 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Brief Summary  

Fresh gas flow reduction to less than 1 L/min during maintenance phase of general anaesthesia is well associated with several benefits. Aggrandized preservation of temperature and humidity, money saving through better utilization of inhaled anesthetic agents, and environmental issues are three basic reasons to implementation of low or minimal-flow anesthesia.

The benefits and feasibility of low-flow anaesthesia have been already suggested for nearly two decades.2In 1995, Baum and Atikenhead3presented that: ‘‘Although there are potential risks associated with low-flow anesthesia, modern anesthesia machines meet all the technical requirements for the safe use of low-flow techniques if they are used in conjunction with equipment for monitoring inhaled and exhaled gas concentrations; these monitors are already increasingly available and, in the near future, are likely to become an obligatory safety standard in many countries. For both economic and ecological reasons, the use of new inhalational anaesthetics, with low tissue solubility and low anesthetic potency, can be justified only if the efficiency of administration is optimized by using low flow anesthetic techniques.’’

New inhaled anaesthetics, sevoflurane and desflurane, have quite low blood and low tissue solubility, which helps in rapid equilibration between the alveolar and effect site (brain) concentrations and makes them ideally suited for low flow techniques. Modern anaesthesia machines are well designed for low flow anaesthesia techniques, which have leak free circle systems, highly efficient CO2absorbers, and the common practice of utilizing on line real-time multi-gas monitor, including essential alarm systems and many more advanced features, allow for safe and cost effective low flow techniques during maintenance of anesthesia.

Few of recent studies also showed that respiratory function and also mucociliary clearance are better preserved with a low flow anesthetic technique as compared with high-flow anesthesia. 

There are no absolute contraindications to utilizing low-flow anesthesia during elective general anesthesia. Keeping in mind the long-time constants of low-flow techniques, it may not be optimal to use low-flow techniques in emergency cases or in medically complex patients where a rapid adjustment of the inhaled anesthetic concentration may be required.

Even though low flow anaesthesia concept is very beneficial and quite easy to learn and practice, it is not so popular in day to day clinical practices even at tertiary care hospital and institute in most of developing countries. Theoretical knowledge and practical implications both are necessary to fulfilling the ultimate aim of any clinical concept. In most of teaching and research institute on floor anaesthesiologists are youngsters like junior and senior anaesthesia residets. Their knowledge and day to day practices towards low flow anaesthesia are very important for actual implications of low flow anaesthesia concept. Therefore, we deiced to assessment of knowledge and practice of low flow anaesthesia by randomly observing their practice in low flow anaesthesia first than we also decided to get their responses via questionnaire.

 For assessment of low flow anaesthesia practice at our tertiary care hospital, we will be observe the total fresh gas flow (ltr/min) and dial setting of inhalational agents randomly during maintenance of surgical anaesthesia without the knowledge of the ground users. We will also made the questionnaire for assessing the knowledge and clinical practice of low flow anaesthesia in day to day practice. We decided to get responses from young anaesthesiologists including junior and senior residents of anaesthesia from our tertiary care research institute of India. 

 
Close