This is a randomized controlled trial among patients who are treated with radiation therapy for diagnosed head and neck cancer at tertiary oncology care centre KMCH, Attavar in Mangalore, South India. Selection of specific “raga” would be according to the inherited knowledge prevailed in centuries in the Indian classical music. This study includes all the patients who were diagnosed with Head and neck squamous cell carcinoma and treated under chemotherapy and radiotherapy at Kasturba Medical College and Hospital. The diagnosis of Head and neck cancer established by histopathologic  study. Demographic details, clinical staging, comorbidity status, treatment, recurrence, follow up data, would also be analyzed along with music therapy outcome. This study excludes those patients who were less than 16 years of age, having hearing deficit, not suitable for CT-R and not willing to consent. Our objectives are to study the effect of specifically selected “raga” in Indian classical music in patients undergoing CT-RT (chemo-RT) for head and neck cancer, analyze the therapeutic use of specific “raga” in Indian classical music in cancer patients and to study the music therapy (specific “raga” in Indian classical music) outcomes. This study would probe into the therapeutic use of Indian classical music among all the head and neck cancer patients taking radiotherapy from the centers of analysis so that the fraction of patients getting this music therapy can be analyzed along. We also look forward to see whether the outcomes had changed with the music therapy which is serious concern in regard to the survival. We will analyze the cases and controls at 0th, 3rd and the 5th/7th week of Radiation using pretested semi-structured questionnaires (Hamilton anxiety rating scale, Hospital anxiety and depression scale and visual analogue scale for pain). The data will be analyzed using SPSS version 17. Results will be expressed in proportions and standard derivations. Chi-square test and t test will be used to test statistical significance.  P value of <0.05 will be considered significant.