Children are more anxious and fearful due to their limited cognitive capabilities, lack of understanding of health care system and lack of self-control. Premedication help to alleviate the stress and fear of treatment as well as to ease child-parent separation and promote smooth induction of anesthesia. The intramuscular, intravenous, subcutaneous and intraosseous routes provide optimal drug delivery, but they are painful and children dislike the needle prick. Multiple agents have been used to treat pre-operative anxiety and stress. New drugs such as the α2 agonists have been introduce as an alternative for premedication in pediatric patients. In our study we aim to compare the effect of intranasal dexmedetomidine and intranasal fentanyl in pediatric patients posted for elective surgery. A total of 88 patients will be randomly allocated into 2 groups with 44 patients in each group. Group D will receive intranasal dexmedetomidine 1µgm/kg and group F will receive intranasal fentanyl 1.5 µgm/kg, 45 minutes prior to induction of anesthesia. Patients will be monitored pre-operatively for vitals parameters including heart rate, blood pressure, oxygen saturation and sedation and child parent separation score. Intra-operatively vitals and post-operatively behavior and sedation score will also be monitored. Possible side- effects of these agents will be monitored and managed. Thereafter, comparison will be made among the two groups based on the data collected. The different variables and occurrence of side effects, if any, would also be noted and compared amongst all groups.