Coronary artery disease (CAD) is the leading cause of the death in the western world presently. The complicated lifestyle choice, unhealthy diet pattern and poor physical activity made its way acutely to India. Lately, non-communicable CAD has substituted tuberculosis, which was the top killer in 199. Coronary heart disease is the most common type of heart disease, it is estimated that every year 2.4 million Indians die due to the coronary heart disease, out of this 30% from the urban and 15 percent from the rural population.

Percutaneous transluminal coronary angioplasty (PTCA) otherwise known as coronary revascularization is the safe and effective treatment of choice in acute coronary syndrome (ACS). Which augments better symptom relief and enhanced quality of life of the patients, thus reduced the mortality rate. The term major adverse cardiac events (MACE) is a commonly used endpoint for cardiovascular research. By definition, MACE is a composite of clinical events and usually includes endpoints reflecting safety and effectiveness.

 ACC/AHA defines MACE as Cardiac death, nonfatal reinfarction, clinically driven target lesion revascularization (TLR) or target vessel revascularization (TVR), stroke and all-cause mortality, which requires unplanned hospitalization or emergency room visit. The incidence of MACE is 30 percent after coronary angioplasty.

Lifestyle modification is indicated for all patients with coronary artery syndrome, irrespective of drug therapy. There is strong evidence that regular physical activity has an independent cardio-protective effect. Un-healthy diet, sedentary life, tobacco abuse, high blood pressure, high blood sugar and blood cholesterol level are identified cardiac risk factors, it is mandatory to avoid those after coronary revascularization with regular follow-up and proper medication for healthy and better quality of life.

An occurrence of MACE in post-angioplasty patients is identified in many international studies, but through this study, we will assess the MACE in South Indian population after the procedure on different follow-ups (1, 6, 12 and 24 months). This study will reveal the important factors which influence the occurrence of the MACE after PTCA.

The aim of current study is to assess the major adverse cardiac events (MACE) and to identify the various factors influencing MACE.

Objectives of the study is 

1. To assess the occurrence rate of MACE among a cohort of post-angioplasty subjects 

2. To evaluate the various influencing factors including anthropometric, social, economic and demographic factors

3. To assess the adherence to lifestyle modification and Health-related quality of life in post-angioplasty patients  

Source of data collection and study material