Intensive programs like lifestyle modifications, drug adherence, exercise, etc. through mobile phone messages to effect significantly reduce or delay the onset of MS. mHealth refers to the utilization of mobile phones and other personal mobile devices as a platform for public health or medical interventions. The present study will be undertaken with the objectives to study the prevalence of MS and to assess the effect of mHealth-MS intervention programme on its selected components in rural population of Rajasthan. A community based intervention study including 4000 subjects’ age 20 years & above will be selected using multi stage cluster sampling method & PRePAre risk assessment study’s questionnaire was used to study risk factors. Each cluster would be 100 participants from each primary sampling unit (PSUs) and total no. of required clusters are 40. In this study comparing [1] standard of care (50% clusters) with standard of care plus a mobile phone based IVRS intervention [50% clusters] for 1 year among patients with MS. IVRS audio messages will be delivered health messages and triggers to promote knowledge, healthy eating, exercise, self-efficacy, and medication adherence for one year. After the development of tools and strategy and assessing the success of this intervention (midterm), research cum action projects will be developed for other regions of the Rajasthan.