Introduction-
Introduction is the preface of the
dissertation which deals with the introduction of Kashatartava (Dysmenorrhea) . It also includes Epidemiology,
Importance of present study, Introduction of drug, list of previous work on present topic, need
of present research work, aims and objectives, material and method and
fundamentals of selection of trial drugs and study design. According to
ayurveda view, Ärtava or menstruation
should not be associated with any sort of discomforts as pain, burning
sensation etc. There is no description of KrichÄrtava
as a disease in Ayurveda classics. The present study is aimed at understanding
Kashtartva as disease and finding out
the treatment.
Conceptual
Study
The conceptual study is further
subdivided into 3 parts
Historical
Review
It covered all the relevant information from
ancient classics to latest treatises which was searched, compiled
systematically. The
references of the disease and drug in the ancient & modern literature are
described here.
Disease Review
Under this section description of Disease according to
Ayurveda (Kashtartava) and Modern
point of view (Dysmenorrhoea) has been given.
It describes about the Pain during menstruation in different yonivyapads,
artava dusti and other gynaecological disorders. Description of kashtartva as
disease in the form of Roga Paá¹…cak i.e. NidÄna, SamprÄpti, PÅ«rvarupa, Rupa,
Upaśaya is done.
Modern perspective of dysmenorrhoea including
Etio-Pathogenesis, Correlation, Types, Symptoms & Signs, Treatment,
Complication and pathways of uterine pain have been described.
Ayurveda Review
Modern Review
Drug
Review
In drug review, detailed description of VijyÄdi Vati and KuberÄká¹£a Vati, which include the entire description about the
ingredients of formulations, including their name, synonyms, family, chemical
composition, pharmaco-dynamics & pharmacological properties including
modern researches related to Dysmenorrhoea. In this chapter pharmacodynamics of
drugs, method of preparation and analytical study also has been discussed. 

Pharmacognostical Study
The main aim of
Pharmacognostical study was to identify dry samples of ingredients of VijyÄdi Vati and
KuberÄká¹£a Vati macroscopically
& microscopically. Pharmacognostical study has been carried out in two
steps; Organoleptic Study and Powder microscopy.
Preparation of Drug
Analytical Study

Organoleptic and physico-chemical parameters,
Qualitative tests for various functional groups, thin layer chromatography were
done and the data are summarized in this section.
Clinical Study

VijyÄdi
Vati and KuberÄká¹£a
Vati were evaluated for their comparative efficacy in patients suffering
KaÅ›tÄrtava. The study was a randomized prospective longitudinal comparative
clinical study in which clinical features of selected patients were assessed
before and after the intervention.
This section comprises of:
Material
and Methods
This Chapter contains detailed description of Aims &
Objects, criteria of selection of patients, Grouping, Criteria for assessment
and method of evaluation of clinical recovery and Management.
Observations
It
comprises the clinical data with observation. Assessment was done on the basis
of a specially designed performa for that purpose. This chapter contains the
incidence of various factors observed in the study.
·
Maximum
98 patients were Yuvati
·
Maximum
49 patients were having Abdomen pain, backache and radiating to thigh.
·
Maximum
54 patients were having spasmodic type of pain.
·
Maximum
52 patients were having onset of pain during menses.
·
Maximum
47 patients were having pain for >1-3 days in each cycle.
·
Maximum
30 patients were having heavy work as aggravating factor for pain.
·
Maximum
47 patients were having H/O taking oral medicines.
·
36
patients were having associated symptoms of grade 3 (7-10 symptoms), 31
patients were of grade 2 (4-6 symptoms), 30 patients were of
grade1(1-3symptoms). 3 patients have no associated symptoms. Result
This section has result from the clinical study
were analyzed statistically to evaluate & compare the efficacy of drug. It was found that Average percentage of relief was
higher in ‘Group A’ i.e. 73.7%, followed
by ‘Group B’ i.e. 59.39%. It shows that effect of therapy was better
in Group A in comparison to Group B.
15.4 Discussion

This section includes the discussion on conceptual review, drug
review, Clinical data obtained from the studies. Here critical discussion on minute details of disease, drug formulations, logical and scientific interpretation of data
obtained during the study and analysis of results have been discussed.
Conclusion
In conclusion possible concluding views and
comments are presented.VijayÄdi Vaá¹i was found
to be more effective on Symptoms which are Pain Intensity, Pain Duration,
Nature, Pain Assessment, Nausea, Vomiting, Fatigue, Head ache, Fainting,
Giddiness, Diarrhoea, Constipation, Vaginal Discharge, Breast Tenderness where
as KuberÄká¹£ha Vaá¹i showed better cure in symptoms which are Menstrual Flow
Amount, Menstrual Flow duration. Statistically there was not much difference in
between the results of two groups. Intergroup comparison of improvement of
symptoms was statistically significant (p<0.05) in case of Pain duration,
Pain Nature, Pain Assessment and Fatigue.
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