Chronic suppurative otitis media (CSOM) is the result of an initial episode of acute otitis media (AOM), followed by chronic infection of middle ear and mastoid mucosa and is characterized by a persistent discharge from the middle ear through a tympanic perforation. It is an important cause of preventable hearing loss, particularly in the developing world. The global burden of illness from CSOM involves 65-330 million individuals with draining ears, 60% of whom suffer from significant hearing impairment. The majority of the homeopathy research studies revealed promising role of homeopathic treatment in otitis media. However, the focus was principally on acute otitis media; and CSOM remained under-researched. This study presents the first prospectively collected data using the Bengali COMOT-15 and effectiveness of individualized homeopathy treatment in CSOM. In this project, we intend to develop translated Bengali version of COMOT-15 through standardized forward-backward translation method, to validate it and test its psychometrics on 100 CSOM patients in the ENT outpatient of Mahesh Bhattacharyya Homoeopathic Medical College & Hospital. Following that, we intend to use it as an outcome measure in an open observation trial testing usefulness of individualized homeopathic treatment in CSOM. The study will start in April 2017 and is estimated to continue up to 2 years. All the patients will be treated with individualized homoeopathic medicines in both centesimal and 50 millesimal potencies as per need of the case. Data will be collected at baseline, after 3 months, and after 6 months. The generated results will be analyzed in the end using appropriate statistical tests and the results will be published in scientific research journals.