CTRI

FULL DETAILS (Read-only) -> Click Here to Create PDF for Current Dataset of Trial

CTRI Number

CTRI/2010/091/000632 [Registered on: 15/06/2010]

Last Modified On:

03/06/2013

Post Graduate Thesis

Type of Trial

Type of Study

Study Design

Single Arm Study

Public Title of Study

To assess the Efficacy and tolerability of Bisoprolol in patients with newly diagnosed Stage I essential hypertension.

Scientific Title of Study

Efficacy and tolerability of Bisoprolol in patients with newly diagnosed Stage I essential hypertension.

Trial Acronym

Secondary IDs if Any

Secondary ID	Identifier
MS/CV-026/01	Protocol Number

Details of Principal Investigator or overall Trial Coordinator (multi-center study)

Name	Dr. Amit Garg
Designation
Affiliation
Address	Merck Serono (Merck Ltd.) Mumbai Shiv Sagar Estate 'A' Dr. Annie Besant Road,Worli Mumbai MAHARASHTRA 400018 India
Phone	02266609044
Fax	02224936046
Email	amit.garg@merck.co.in

Details of Contact Person
Scientific Query

Name	Dr. Amit Garg
Designation
Affiliation	Head- Medical services
Address	Merck Serono (Merck Ltd.) Mumbai Shiv Sagar Estate 'A' Dr. Annie Besant Road,Worli Mumbai MAHARASHTRA 400018 India
Phone	02266609044
Fax	02224936046
Email	amit.garg@merck.co.in

Details of Contact Person
Public Query

Name	Dr. Amit Garg
Designation
Affiliation
Address	Merck Serono (Merck Ltd.) Mumbai Shiv Sagar Estate 'A' Dr. Annie Besant Road,Worli Mumbai MAHARASHTRA 400018 India
Phone	02266609044
Fax	02224936046
Email	amit.garg@merck.co.in

Source of Monetary or Material Support

Merck Serono (Merck Ltd.), Shiv Sagar Estate 'A' Dr. Annie Besant Road Worli, Mumbai 400 018

Primary Sponsor
Modification(s)

Name	Merck Serono Merck Ltd
Address	Shiv Sagar Estate ADr. Annie Besant RoadWorli, Mumbai 400 018
Type of Sponsor	Pharmaceutical industry-Indian

Details of Secondary Sponsor

Name	Address
NIL

Countries of Recruitment

India

Sites of Study

No of Sites = 275
Name of Principal Investigator	Name of Site	Site Address	Phone/Fax/Email
DR. SUNNY ORATHEL	HOSPITAL ERNAKULAM GENERAL	,- Ernakulam KERALA
DR. VINOD KRISHNAN	A K G MEMORIAL COOPERATIVE HOSPITAL	,- Kannur KERALA
DR. MANOJ AGGARWAL	AGGARWAL HEART & SURGICAL HOSPITAL	,-
DR. RAJKUMAR GUPTA	AGRA MEDICITY	,- Agra UTTAR PRADESH
DR. ANIL SALEEM K	ALSHIFA HOSPITAL	,-
DR. ANANT SAXENA	AMAR ASHISH HOSPITAL	,- New Delhi DELHI
DR. W BOBBY MOSES	ANANTHAPURI HOSPITAL & RESEARCH INSTITUTE	,-
DR. N PARRY	ANBU HOSPITAL	,-
DR. N PARRY	ANBU HOSPITAL	,-
DR. ATUL ARORA	ATUL CLINIC	,- Kurukshetra HARYANA
DR. AMRUT SUTHAR	AVARDA HOSPITAL	,-
DR. ASHFAQUE AHMED	B S G HOSPITAL	,-
DR. S K BHAGANIA	BHAGANIA CLINIC	MAIN ROAD,JHARIA-828111 Dhanbad JHARKHAND	03262461490 drskbhagania@gmail.com
DR. V CHANNARAYA	BHARATHI NURSING HOME	,- Bangalore KARNATAKA
DR. MANOJ SOLANKI	BHAVNA HOSPITAL	,-
DR. J NAMBIRAJAN	BRINDHAVAN CLINIC	,- Chennai TAMIL NADU
DR. ANIRUDDHA GHORAI	C D HOSPITAL	,-
DR. H N RAJENDRA KUMAR	CHANDANA HOSPITAL	,- Bangalore KARNATAKA
DR DIPANKAR	CHARITABLE HEART CARE CENTRE	DEB,-
DR PARIMAL SARKAR	CHARU PATHOLOGY	,-
DR. UDAY B NAYAK	CLINIC	GURU PLAZA COMPLEX,NR. KSRTC BUS STAND, BEJAI- Bangalore KARNATAKA	09845079262
DR. SUDHIR BS	CLUMAX DIAGNOSIS	,- Bangalore KARNATAKA
DR. SAMEER DUMIR	CRITI CARE	,- Mumbai MAHARASHTRA
DR O K BORGOHAIN	DAMANI MEDICAL STORE	,- Sibsagar ASSAM
DR. SANJAY ARORA	DANGE CLINIC	,- Lucknow UTTAR PRADESH
DR. AJAY VINAYAK RAO DAPHALE	DAPHALE HOSPITAL	,- Amravati MAHARASHTRA
DR. ASHOK KUMAR SRIVASTAVA	DCNH HOSPITAL	,- Gorakhpur UTTAR PRADESH
DR. M LOGANATHAN	DHANANJAI POLYCLINIC	,- Salem TAMIL NADU
DR. M LOGANATHAN	DHANANJAI POLYCLINIC	,- Salem TAMIL NADU
DR. S R RANGABASHYAM	DHARAN HOSPITAL	,- Salem TAMIL NADU
DR. S R RANGABASHYAM	DHARAN HOSPITAL	,- Salem TAMIL NADU
DR. M PALANIAPPAN	DHIYANALINGA POLYCLINIC	,- Madurai TAMIL NADU
DR. GAUTAM DAS	DOCTORS CLINIC	,-
DR. RAJIV BABANRAO DONGRE	DONGARE HOSPITAL	,- Aurangabad BIHAR
DR MANMATH NATH	DR NATH CLINIC	,-
DR. SANJAY PANDEY	DR PANDEY CLINIC	,- Korba CHHATTISGARH
DR. DHEERAJ VERMA	DR VERMA CLINIC	,- Jaipur RAJASTHAN
DR. SHAHID ABBAS	DR. ABBAS CLINIC	,- Indore MADHYA PRADESH
DR. SHAHID ABBAS	DR. ABBAS CLINIC	,- Indore MADHYA PRADESH
DR. ANIL AGARWAL	DR. AGARWAL CLINIC	,- Gwalior MADHYA PRADESH
DR. ANIL AGARWAL	DR. AGARWAL CLINIC	,- Gwalior MADHYA PRADESH
DR. VIJAY KUMAR AGARWAL	DR. AGARWAL CLINIC	,- Agra UTTAR PRADESH
DR. ANIL ADYA	DR. ANIL ADYA	,-110018 New Delhi DELHI
DR. ANIL GUPTA	DR. ANIL GUPTA	,- New Delhi DELHI
DR. N MD ATHAULLAH	DR. ATHAULLAH	,- Hyderabad ANDHRA PRADESH
DR. B N JHA	DR. B N JHA	GAUSHALA ROAD,,P O RAMNA-842002 Muzaffarpur BIHAR	06212281737 jhadrbn12@rediffmail.com
DR. B RAMESH BABU	DR. B RAMESH BABU	,- Erode TAMIL NADU
DR. JASWINDER SINGH	DR. BABA SAHEB AMBEDKAR HOSPITAL	SECTOR-6,ROIHNI-110085 New Delhi DELHI
DR. SHAILENDRA KAUSHIK	DR. BABA SAHEB AMBEDKAR HOSPITAL	,-63 New Delhi DELHI
DR. INDRANEEL BASU	DR. BASU CLINIC	,-
DR. SHIVRAM BHONAGIRI	DR. BHONAGIRI CLINIC	,- Pune MAHARASHTRA
DR. V K BINDRA	DR. BINDRA CLINIC	,- Meerut UTTAR PRADESH
DR. PRABIR KUMAR BISWAS	DR. BISWAS CLINIC	,- Kolkata WEST BENGAL
DR. DIPAK BORBORA	DR. BORBORA CLINIC	,-
DR MANOSHEE BOROOWA	DR. BOROOWA CLINIC	,- Lakhimpur ASSAM
DR. GAURAV BUCH	DR. BUCH CLINIC	,- Rajkot GUJARAT
DR. P CHIDAMBARANATHAN	DR. CHIDAMBARANATHAN CLINIC	,-
DR. DEBASIS HALDER	DR. DEBASISH HALDER	,-736101
DR. VAIBHAV DEDHIA	DR. DEDHIA CLINIC	,- Mumbai MAHARASHTRA
DR. DEVENDRA SINHA	DR. DEVENDRA SINHA	,-
DR. VIVEK DUBEY	DR. DUBEY CLINIC	,-
DR. VIVEK DUBEY	DR. DUBEY CLINIC	,-
DR. KABIR DUTTA	DR. DUTTA CLINIC	,- Kolkata WEST BENGAL
DR. G S SIVAKUMAR	DR. G S SIVAKUMAR CLINIC	,- Madurai TAMIL NADU
DR. GAGANDEEP GAMBHIR	DR. GAMBHIR CLINIC	,- Udaipur RAJASTHAN
DR. PRAKASH GANDHI	DR. GANDHI CLINIC	,-
DR. ASHOK GARG	DR. GARG''S WOMAN CLINIC AND HEART CARE CENTRE	,- Jaipur RAJASTHAN
DR. GAUTAM SARKAR	DR. GAUTAM SARKAR CLINIC	,- Kolkata WEST BENGAL
DR. PRASHANT GOVARDHAN	DR. GOVARDHAN CLINIC	,- Nagpur MAHARASHTRA
DR. GOVIND RAJAN	DR. GOVIND RAJAN CLINIC	,-
DR. PRAVEEN GUPTA	DR. GUPTA CLINIC	,- Firozabad UTTAR PRADESH
DR. GURBEER SINGH SEHGAL	DR. GURBEER SINGH SEHGAL CLINIC	,-
DR. GYANCHANDALI T K	DR. GYANCHADANI CLINIC	,- Bhopal MADHYA PRADESH
DR. T K GYANCHANDANI	DR. GYANCHANDANI CLINIC	,- Bhopal MADHYA PRADESH
DR. J K ARYA	DR. J K ARYA	,-
DR. P JAMBULINGAM	DR. JAMBULINGAM CLINIC	,-
DR. SONAL KUMAR KADAM	DR. KADAM CLINIC	,- Kolhapur MAHARASHTRA
DR. VINAYAK KALE	DR. KALE CLINIC	,- Pune MAHARASHTRA
DR. J K KANSAL	DR. KANSAL CLINIC	,- Meerut UTTAR PRADESH
DR. VISHAL KASTWAR	DR. KASTAWAR CLINIC	,- Jabalpur MADHYA PRADESH
DR. VISHAL KASTWAR	DR. KASTWAR CLINIC	,- Jabalpur MADHYA PRADESH
DR. AMITABH M KENY	DR. KENY'S NURSING HOME	,- Mumbai MAHARASHTRA
DR. DURGESH KHEMCHANDANI	DR. KHEMCHANDANI CLINIC	,- Bhopal MADHYA PRADESH
DR. KRISHNA KUMAR	DR. KRISHNA KUMAR CLINIC	,-
DR. SANJAY G KUBAWAT	DR. KUBAWAT CLINIC	,- Junagadh GUJARAT
DR. R K MAHAPATRA	DR. MAHAPATRA	,-
DR. BANKE BIHARI MAHESHWARI	DR. MAHESHWARI CLINIC	,- Meerut UTTAR PRADESH
DR. SUSHMA MALPANI	DR. MALPANI CLINIC	,- Mumbai MAHARASHTRA
DR. MOHIT KUMAR SANTRA	DR. MOHIT SANTRA	,-736122
DR. MANABENDRA NAYAK	DR. NAYAK CLINIC	,-
DR. PRAVIN NINAVARE	DR. NITNAVARE CLINIC	,- Nagpur MAHARASHTRA
DR. CHIDAMBARANATHAN	DR. P CHIDAMBARANATHAN	,-
DR. P JAMBULINGAM	DR. P JAMBULINGAM CLINIC	,-
DR. B PALANI	DR. PALANI CLINIC	,- Chennai TAMIL NADU
DR. ALOK PANDE	DR. PANDE CLINIC	,- Gwalior MADHYA PRADESH
DR. ALOK PANDEY	DR. PANDEY CLINIC	,- Gwalior MADHYA PRADESH
DR. PARAMARTHA BHATTACHARYA	DR. PARAMARTHA BHATTACHARYA	,-
DR. PRAMOD PAL SEHGAL	DR. PRAMOD PAL	RAJOURI,-110027 New Delhi DELHI
DR. SHYAM PRASAD	DR. PRASAD CLINIC	,- Hyderabad ANDHRA PRADESH
DR. RAJESH KUMAR JHA	DR. RAJESH KUMAR JHA	BENTA CHOWK,LAHERIASARAI- Darbhanga BIHAR	09430063479 rajeshjhadbg@yahoo.co.in
DR. LACHAN JOSHI	DR. RAJIV LOCHAN JOSHI CLINIC	,-
DR. V RAJKUMAR	DR. RAJKUMAR CLINIC	,- Salem TAMIL NADU
DR. RAMPAL VIDHWAN	DR. RAM PAL VIDHAWAN CLINIC	,-
DR. B RAMESH BABU	DR. RAMESH BABU CLINIC	,- Erode TAMIL NADU
DR. MADYANAM VIJAYAMOHAN RAO	DR. RAO CLINIC	,-
DR. MADYANAM VIJAYMOHAN RAO	DR. RAO CLINIC	,-
DR. V VIWESWARA RAO	DR. RAO CLINIC	,- Hyderabad ANDHRA PRADESH
DR. MANOHAR RATHOD	DR. RATHOD CLINIC	,- Mumbai MAHARASHTRA
DR. A RIYAS	DR. RIYAS CLINIC	,- Kollam KERALA
DR. PRAKASH RAMANAGOUDAR	DR. S R RAMANAGOUDAR MULTISECIALITY HOSPITAL & RESEARCH INSTITUTE	MALAPUR ROAD,DHARWAD-580001 Dharwad KARNATAKA	08362228236
DR. V S SAJITH	DR. SAJITH CLINIC	,-
DR. MANOJ SALUJA	DR. SALUJA CLINIC	,- Kota RAJASTHAN
DR. SANJOY BHATTACHARYA	DR. SANJOY BHATTACHARYA	,- Kolkata WEST BENGAL
DR. SATISHCHANDRAN	DR. SATISHCHANDRAN CLINIC	,-
DR. SATISHCHANDRAN	DR. SATISHCHANDRAN CLINIC	,-
DR. P SELVAPANDIAN	DR. SELVAPANDIAN CLINIC	,- Chennai TAMIL NADU
DR. I S SHARMA	DR. SHARMA CLINIC	,- Nanded MAHARASHTRA
DR. SHAUNAK MEHTA	DR. SHAUNAK MEHTA	203, TRADE HOUSE,ATHUGAR STREET, NANPURA- Surat GUJARAT	02612472116 drspm2000@yahoo.com
DR. SUNIL SINGHVI	DR. SINGHVI CLINIC	,- Chennai TAMIL NADU
DR. S K ARORA	DR. SK ARORA	SHALIMAR BAGH,-88 New Delhi DELHI
DR. SHAILESH SRIVASTAVA	DR. SRIVASTAVA CLINIC	,- Lucknow UTTAR PRADESH
DR. K SUDEEP	DR. SUDEEEP CLINIC	,- Kannur KERALA
DR. SUNIL KUMAR	DR. SUNIL KUMAR	G 19, P C COLONY,KANKARBAGH-800020 Patna BIHAR	09431011920
DR. SURESH CHANDRA GUPTA	DR. SURESH CHANDRA GUPTA	DDA MARKET,PITAMPURA-34 New Delhi DELHI
DR. SURYANARAYANA MURTHY	DR. SURYANARAYANA MURTHY CLINIC	,- Hyderabad ANDHRA PRADESH
DR. TANMAY CHOUDHARY	DR. TANMAY CHOUDHARY	,- Kolkata WEST BENGAL
DR. TAPAN CHAKRABORTY	DR. TAPAN CLINIC	,- Kolkata WEST BENGAL
DR. TAPAS CHATTERJEA	DR. TAPAS CHATTERJEA	,- Kolkata WEST BENGAL
DR. K D TIBREWALA	DR. TIBREWALA CLINIC	,- Ahmadabad GUJARAT
DR. TUSHAR KANT CHANDRA	DR. TUSHAR CHANDRA	,-736101
DR. T V VENKATESWARAN	DR. VENKATESWARAN CLINIC	,- Thrissur KERALA
DR. VENUGOPALA D	DR. VENUGOPALA D	,-575003 Bangalore KARNATAKA	08242495208 drvenugopala@gmail.com
DR. S C WADHWANI CLINIC	DR. WADHWANI CLINIC	,-
DR. WASNIK DADARAO SHRIRANG	DR. WASNIK CLINIC	,- Chandrapur MAHARASHTRA
DR. YOGINDER GUPTA	DR. YOGINDER GUPTA	,PASCHIM VIHAR-63 New Delhi DELHI	01125275556
DR. AJAY DUBEY	DUBEY HOSPITAL	,-
DR. AJAY DUBEY	DUBEY HOSPITAL	,-
DR. DURGESH KHEMCHANDANI	DURGESH HOSPITAL	,- Bhopal MADHYA PRADESH
DR. GEORGE THATCHIL	ERNAKULAM MEDICAL CENTRE	,-
DR. K V MALLIKHARJUN RAO	EVYA CLINIC	,- Hyderabad ANDHRA PRADESH
DR. BHAVIN V FALDU	FALDU DIAGNOSTIC AND HOSPITAL	,- Junagadh GUJARAT
DR. SYED SULTAN IBRAHIM	FATHIMA CLINIC	,-
DR. V RAJKUMAR	G V H HOSPITAL	,- Salem TAMIL NADU
DR. ASHOK JAIN	GANDHI POLYCLINIC	,- Dhar MADHYA PRADESH
DR. ASHOK JAIN	GANDHI POLYCLINIC	,- Dhar MADHYA PRADESH
DR. VINOD BHATT	GAYATRI MEDICARE	,-
DR. NARAHARI MG	GEETA MEDICARE	#1498-6B,SARADAVILAS COLLEGE ROAD,- Mysore KARNATAKA	09448078704
DR. G MANOJ	GENERAL HOSPITAL	,- Ernakulam KERALA
DR MANISH SHRIVASTAVA	GITANJALI CLINIC	,-
DR. HANSRAJ SUMAN	GOVT HOSPITAL	,- Baran RAJASTHAN
DR. CHANDRASHEKHAR	GS DIABETES CLINIC	#358/1, 8TH MAIN,P J EXTENSION-577002	08192231487
DR. VINAY BHAT	HARMUKH CLINIC AND DIAGNOSTIC	,-
DR. DINESH SHARMA	HBK2 HOSPITAL	,- Jaipur RAJASTHAN
DR. SUDHIR KUMAR SINGH	HEALTH N' HOME	,-826004 Dhanbad JHARKHAND	03262201178
DR. KRISHNA KUMAR BARUN	INDIRA GANDHI INSTITUTE OF CARDIOLOGY	,- Patna BIHAR
DR. KRISHNA KUMAR BARUN	INDIRA GANDHI INSTITUTE OF CARDIOLOGY	,- Patna BIHAR
DR. RAJNIKANT MOVALIYA	JALARAM HOSPITAL	3RD FLOOR, DOCTOR HOUSE, SARGAM COMPLEX,VARACHHA ROAD- Surat GUJARAT	02612559298
DR. S CHANDRASEKHAR	JAYASELVAM CLINIC	,- Chennai TAMIL NADU
DR. ARVIND KUMAR	JEEVAK HEART HOSPITAL & RESEARCH INSTITUTE	6, DOCTORS COLONY,KANKARBAGH-800020 Patna BIHAR	09835085231
DR. JOTHI PALAKSHI	JOTHI PUTTAPPA MEMORIAL CLINIC	,- Dharwad KARNATAKA
DR. RAJESH KAKKAR	KAKKAR MEDICAL CENTRE	,- Gurgaon HARYANA
DR. NAVEEN AGARWAL	KALAWATI MEDICAL	,-
DR. VIVEK KATIYAR	KATIYAR CLINIC	,- Lucknow UTTAR PRADESH
DR. G K KHURANA	KHURANA CLINIC	,- Faridabad HARYANA
DR. PRAKASH BABALICHE	KLE'S CITY POLY CLINIC	OPP. CORPORATION BANK,SAMADEVI GALLI-590001 Belgaum KARNATAKA	09343635679
DR. AMAR MODI	KRISHNA HOSPITAL	C M CHAMBERS,CHHANI-	02652760131
DR. RAJESH SARODE	KRISHNA HOSPITAL	,- Wardha MAHARASHTRA
DR. O MUTHUKUMAR	KUMAR HOSPITAL	,-
DR. PRAKASH DHARANA	LEELA HOSPITAL	MANVI BUILDING,COURT ROAD-582101 Gadag KARNATAKA	08372252983
DR. DILIP AGRAWAL	LILAVATI HEARTCARE & MEIDCAL HOSPITAL	,-
DR RAHUL DESHPANDE	LOKMANGAL HOSPITAL	KUMBHARI AKKALKOT ROAD,-413002 Solapur MAHARASHTRA	09769667849
DR. ABRAHAM GEORGE	LOURDES HOSPITAL	,-
DR. A ASRAF ALI	M A G CLINIC	,-
DR. ASRAF ALI	MAG CLINIC	,-
DR. A R PATHAN	MAHARAV BHIMSINH HOSPITAL	,- Kota RAJASTHAN
DR. A JAYABAL	MALAR SPECIALITY CLINIC	,- Salem TAMIL NADU
DR. A JAYABAL	MALAR SPECIALITY CLINIC	,- Salem TAMIL NADU
DR. SANJAY SHAH	MALAY MEDICAL & HEART HOSPITAL	,-
DR. RAMANAND MALI	MALI(BHADEKAR) HOSPITAL & ICU PARBHANI	,- Parbhani MAHARASHTRA
DR. L NARENDRA PRASAD	MANASVI SPECIALISTS	,- Bangalore KARNATAKA
DR. RAM LONDHE	MAULI HOSPITAL	,- Aurangabad BIHAR
DR. M SOMASUNDER	MEENAM HOSPITAL	,- Chennai TAMIL NADU
DR. VISHAL MEHRA	MEHRA HOSPITAL	,-
DR. P JEGAN	MENAKA HOSPITAL	,-
DR. SANJEEVA GUPTA	MGS HOSPITAL	PUNJABI BAGH,- New Delhi DELHI	sanjeeva_gupta@rediffmail.com
DR. M H SUBRAMANIAM	MIMS HOSPITAL	,-
DR. ATANU GHOSH	MY CLINIC	,-
DR. A B TARAFDAR	N F RLY HOSPITAL	,-
DR. NISHITH VYAS	N M VIRANI WOCKHARDT HOSPITAL	,- Rajkot GUJARAT
DR. SEENAJ CHANDRAN	NAJATH SUPER SPECIALITY HOSPITAL	,-
DR. G R NEVLEKAR	NEVLEKAR HOSPITAL	,- Pune MAHARASHTRA
DR RASHITA UPADHYAYA	NIHAR MEDICAL	,- Tinsukia ASSAM
DR. H AGARWAL	NORTH VIEW CLINIC	,-
DR. ATMARAM V P	OKAY MISSION HOSPITAL	,-
DR. ASHOK KUMAR YG	OKUDE DIAGNOSTIC & MEDICAL CENTRE	OPP. BHARAT PETROL PUMP,KUNJIBETTU-576102 Udupi KARNATAKA	09845243606 drashokude@rediffmail.com
DR. C A SASIKUMAR	PADMAVATHY MEDICAL FOUNDATION	,- Kollam KERALA
DR. PARTHA GUHANEOGI	PARAMITA MEDICAL	,-
DR. RAVI KUMAR	PATEL HOSPITAL	,- Jalandhar PUNJAB
DR. PANKAJ KUMAR JAIN	POLY CLINIC	,- Kota RAJASTHAN
DR. MANOJ PUJAR	POOJA HOSPITAL	3RD MAIN ROAD,,PJ EXTN,-577002	08192250312
DR. SANTHOSH K R	PRS HOSPITAL	,-
DR. SANTHOSH KR	PRS HOSPITAL	,-
DR. GEORGE KOSHY	PUSHPAGIRI HOSPITAL	,-
DR. GEORGE P KOSHY	PUSHPAGIRI HOSPITAL	,-
DR. K P HASIM	RASHIDALE	,-
DR. RAJENDRA RAWEKAR	RAWEKAR HOSPITAL	,- Wardha MAHARASHTRA
DR. P BALAN	RHYATHAM HOSPITAL	,-
DR MURUGESAN	ROHINI HOSPITAL	,- Thanjavur TAMIL NADU
DR. SABIR KHAN	SABA CLINIC	,- Jaunpur UTTAR PRADESH
DR. HARISH K V	SAGAR CLINIC	,- Bangalore KARNATAKA
DR. T S RAMASWAMY	SAI NURSING HOME	,- Palakkad KERALA
DR. BIRENDRA NATH THAKUR	SANCTORIA HOSPITAL	,-
DR. SANJAY SANGHAVI	SANGHAVI HOSPITAL AND DENTAL CLINIC	,- Dhule MAHARASHTRA
DR. SANJAY BHAGWANDAS TIWARI	SANJEEVAN HOSPITAL	,- Nashik MAHARASHTRA
DR. MANMEET SINGH	SANJIVANI HOSPITAL	,-
DR. R R BHATTACHARYA	SANKALP	,-834002 Ranchi JHARKHAND	06512502662
DR. SUNIL KUMAR JALODIA	SAPRA HOSPITAL	,- Hisar HARYANA
DR. RAJARSHI SARMA	SARMA MEDICAL	MAIN ROAD,BISTUPUR-831001	06572221311 rajusarma@gmail.com
DR. GOPAL D	SAROJ HOSPITAL	BENAKA CLINIC,G H ROAD- Mandya KARNATAKA	09886023049 drgopald@gmail.com
DR. JUDHISTHIR DAS	SEBAYAN	,-
DR. M A BHAT	SENTHIL NURSING HOME	,- Chennai TAMIL NADU
DR. RAM BILAS GOYAL	SEWAK SABHA CHARITABLE HOSPITAL	,- Hisar HARYANA
DR. M D CHHABRA	SEWAK SABHA CHARITABLE TRUST HOSPITAL	,- Hisar HARYANA
DR. MAYANK SHAH	SHAH HEART AND MEDICAL HOSPITAL	,-
DR. A SHAJI	SHAJI CLINIC	,-
DR. MANAOHAR KN	SHARADA DIABETES CENTRE	,- Bangalore KARNATAKA
DR. NILAY DESAI	SHARV MEDICAL HOSPITAL	2ND FLOOR, DEVI PLAZA,ANAND MAHAL ROAD- Surat GUJARAT	02612798600
DR. MUKUND PENURKAR	SHASWAT MULTI SPECIALTY HOSPITAL	,- Pune MAHARASHTRA
DR. PRAKASH KURMI	SHIVAM HOSPITAL	,- Ahmadabad GUJARAT
DR. UMESH GEDIYA	SHIVAM MEDICAL AND NURSING HOME	,- Surendranagar GUJARAT
DR ATUL CHANDRA SAIKIA	SHIVAM MEDICOS	,- Sonitpur ASSAM
DR. J D WAGHELA	SHREE NARAYAN HOSPITAL	,- Akola MAHARASHTRA
DR. ARVIND J MATANG	Shree Radhe Hospital & ICCU	NEAR ST BUS STATION,ANJAR-	02836245199
DR. JAYAPRAKASH APPAJIGOL	SHREE SPECIALITY CLINIC	BASAVA GURUKUL COMPLEX,ANJANEY NAGAR- Belgaum KARNATAKA	09448036185
DR. TAHER HUSSAIN ASSADI	SMRUTHI MULTI SPECIALTY CENTRE	,- Bangalore KARNATAKA
DR. YOGESH SOMANI	SOMANI HOSPITAL	,-
DR CHANDAN SARMAH	SRI KRISHNA MEDICAL	,- Tinsukia ASSAM
DR. M MALLESWARA	SRI RAJESWARI NURSING HOME	,-
DR. VINU JACOB S	SRI RAMAKRISHNA ASRAMA CHARITBLE HOSPITAL	,-
DR. G PAVAN KUMAR REDDY	SRI SAI BALAJI HOSPITAL	,- Hyderabad ANDHRA PRADESH
DR. M SAKTHIRAJ	SRI SAKTHI CLINIC	,-
DR. MANISH SHARMA	SRI SATI MEDI CARE	GH6, FLAT NO 385,PASCHIM VIHAR-87 New Delhi DELHI	09868150079
DR. M SAKTHIRAJ	SRI SHAKTHI CLINIC	,-
DR. CH. BHASKAR RAO	SRI SURYA HOSPITAL	,- Srikakulam ANDHRA PRADESH
DR. T RAMA GURREDDY	SRI VENKATESHWARA CENTER	,-
DR. S VIJAY ALAGAPPAN	SRM HOSPITAL PVT LTD	,-
DR. SAJID ANSARI	SS HEART CARE CENTRE	,- Lucknow UTTAR PRADESH
DR. ALOKE KUMAR CHAUDHAURI	SSKH HOSPITAL	,-
DR. INDRANIL DAS	SSKM HOSPITAL	,- Kolkata WEST BENGAL
DR. M S VARGHESE	ST JOSEPH HOSPITAL	,-
DR. HIMANGSU S PAUL	STEEL CITY NURSING HOME	,-831001	06572232298
DR. BISWAJIT DAS	SUBHAM HOSPITAL	,-736101	03582228754 dr_bdas@rediffmail.com
DR. V MANAKAVALAPERUMAL	SUGHAM HEALTH CENTRE	,- Tirunelveli TAMIL NADU
DR. GOVINDARAJU	SUNDARAM MEDICARE CENTRE	,-
DR. P GOVINDARAJU	SUNDARAM MEDICARE CENTRE	,-
DR. ANKUR RANA	SUSHRUSHA HOSPITAL	BEHIND ASHAPURI MATA MANDIR, SARDAR CHOWK,VIJALPORE- Navsari GUJARAT	02637252208
DR. SANJAY ANDHERE	SUSHRUT CLINIC	,-
DR. YOGESH SUBHASH GOSAI	SWARAJ HOSPITAL	,- Nashik MAHARASHTRA
DR. RAJEEV AGARWAL	SWASTHYA HOSPITAL	,- Gwalior MADHYA PRADESH
DR. RAJIV AGRAWAL	SWSTHYA HOSPITAL	,- Gwalior MADHYA PRADESH
DR. DINESH KUMAR	THE COONOOR DIABETES CENTRE	,-
DR. V DINESH KUMAR	THE COONOOR DIABETES CENTRE	,-
DR. TRILOK RANJAN SRIVASTAVA	UDAI MEDICAL CENTRE	,- Gorakhpur UTTAR PRADESH
DR. DEBASIS MITRA	ULTIMUS CLINIC	,- Kolkata WEST BENGAL
DR. VIRAL PATEL	UMIYA HEART AND MEDICAL HOSPITAL & ICCU	,-
DR. YATIN JOAG	UNIQUE HOSPITAL	,- Solapur MAHARASHTRA
DR. MAHESAN N	V S M HOPSITAL	,-
DR. MAHESAN N	V S M HOSPITAL	,-
DR. DINESH DADA	VASAL HOSPITAL	,- Jalandhar PUNJAB
DR. S P VINOD KUMAR	VENKATESHWARA CLINIC	,- Hyderabad ANDHRA PRADESH
DR. R RAMESH	VICTORY CLINIC	,- Madurai TAMIL NADU
DR. V UMAPATHY	VIJAYA HEART FOUNDATION	,- Chennai TAMIL NADU
DR. MAHESH B SONI	YASHDEEP HOSPITAL	,- Parbhani MAHARASHTRA
DR. MUDIT MOHAN	YASHODA HOSPITAL	,- Ghaziabad UTTAR PRADESH
DR. KISHOR ANANTRAO JADHAV	YASHWANT HOSPITAL	,-

Details of Ethics Committee

No of Ethics Committees= 1
Name of Committee	Approval Status
Unique Independent Ethics Committee	Approved

Regulatory Clearance Status from DCGI

Status

Not Applicable

Health Condition / Problems Studied

Health Type	Condition
Patients	Stage I essential hypertension,

Intervention / Comparator Agent

Type	Name	Details
Intervention	Bisoprolol	starting dose = 2.5 mg and the upper recommended limit is 10mg once a day
Comparator Agent	NIL	NIL

Inclusion Criteria
Modification(s)

Age From	18.00 Year(s)
Age To	60.00 Year(s)
Gender	Both
Details	1 Newly diagnosed JNC 7 Stage I essential hypertension 2 Patient advised CONCOR (Bisoprolol) 3 No other clinically significant co-morbidities

ExclusionCriteria

Details

1 Any contraindications to CONCOR 2 Uncontrolled diabetes (Any ongoing symptoms or complication related to Diabetes) 3 Females in childbearing age not willing to use a reliable mean of contraception 4 Confirmed diagnosis of any CVD except Hypertension

Method of Generating Random Sequence

Not Applicable

Method of Concealment

Not Applicable

Blinding/Masking

Not Applicable

Primary Outcome

Outcome	TimePoints
Percentage of patients achieving BP < 140/ 90 mm Hg	At the end of 12 weeks(responder).

Secondary Outcome

Outcome	TimePoints
(1) Average reduction in systolic and diastolic BP. (2) Average time to reach target BP (in responders). (3) Average dose required to control (in responders). (4) Average reduction in Heart Rate. (5) Assessment of compliance at 12 weeks (pill count). (6) Blood Glucose parameters. (7) Renal parameter status	At the end of 12 weeks(responder).

Target Sample Size
Modification(s)

Total Sample Size="2000"
Sample Size from India="2000"
Final Enrollment numbers achieved (Total)= ""
Final Enrollment numbers achieved (India)=""

Phase of Trial

Phase 4

Date of First Enrollment (India)

Date Missing

Date of Study Completion (India)

Date Missing

Date of First Enrollment (Global)

01/06/2010

Date of Study Completion (Global)

Date Missing

Estimated Duration of Trial

Years="0"
Months="6"
Days="0"

Recruitment Status of Trial (Global)
Modification(s)

Completed

Recruitment Status of Trial (India)

Completed

Publication Details

Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?

Brief Summary

This is a Non randomized, uncontrolled, observational study To assess the Efficacy & Tolerability of CONCOR in patients with newly diagnosed Stage I essential hypertension according to JNC 7 all over India across 300 centres.