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CTRI Number  CTRI/2026/02/102838 [Registered on: 03/02/2026] Trial Registered Prospectively
Last Modified On: 02/02/2026
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Dentistry 
Study Design  Randomized, Parallel Group Trial 
Public Title of Study   oil pulling 
Scientific Title of Study   “Comparative Evaluation of Oil Pulling and Chlorhexidine mouthwash in Reducing dental Plaque and Gingival Inflammation: A Randomized Control Trial” 
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Sakshi Gujarathi 
Designation  PG student 
Affiliation  Sri Aurobindo College of Dentistry, Indore 
Address  104- Maa Vaishno girls hostel,behind luv khush supermarket,near aurobindo hsopital ,indore

Indore
MADHYA PRADESH
453555
India 
Phone  07083305408  
Fax    
Email  smg240600@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  Sakshi Gujarathi 
Designation  PG student 
Affiliation  Sri Aurobindo College of Dentistry, Indore 
Address  104- Maa Vaishno girls hostel,behind luv khush supermarket,near aurobindo hsopital ,indore


MADHYA PRADESH
453555
India 
Phone  07083305408  
Fax    
Email  smg240600@gmail.com  
 
Details of Contact Person
Public Query
 
Name  Sakshi Gujarathi 
Designation  PG student 
Affiliation  Sri Aurobindo College of Dentistry, Indore 
Address  104- Maa Vaishno girls hostel,behind luv khush supermarket,near aurobindo hsopital ,indore


MADHYA PRADESH
453555
India 
Phone  07083305408  
Fax    
Email  smg240600@gmail.com  
 
Source of Monetary or Material Support  
NIL 
 
Primary Sponsor  
Name  sakshi gujarathi 
Address  SRI AUROBINDO COLLEGE OF DENTISTRY 
Type of Sponsor  Private hospital/clinic 
 
Details of Secondary Sponsor  
Name  Address 
SAIMS  DEPARTMENT OF PUBLIC HEALTH DENTISTRY 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
SAKSHI  SRI AUROBINDO COLLEGE OF DENTISTRY  department of public health dentistry
Indore
MADHYA PRADESH 
7083305408

smg240600@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
SAIMS  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Healthy Human Volunteers  PRESENCE WITH STAIN AND CALCULUS 
 
Intervention / Comparator Agent  
snoIntervention/ComparatorTypeDrug-TypeProcedure NameDetails
1Intervention ArmProcedure-oil gargling (Procedure Reference: , Procedure details: gargling with oil 10ml of oil for 5-10 min)
 
Inclusion Criteria  
Age From  18.00 Year(s)
Age To  60.00 Year(s)
Gender  Both 
Details  • Participants of age 18 and above
• Able to provide informed consent
• Expected to comply with the protocol.
• Planning to remain at their current address for the next 6 months.
• No history of dental visit in past 6 months.
 
 
ExclusionCriteria 
Details  • Uncooperative patients/patient who is not willing to give consent
• Existing soft tissue damage caused by ill-fitting dental appliances.
• Participants with systemic diseases and under medication for the same.
• Presence of any dental condition which needed prompt professional attention such as: periodontal disease, dental abscess, pain and swelling.
• Using any other commercially available mouthwash
• Participants having any adverse habits. 
 
Method of Generating Random Sequence   Random Number Table 
Method of Concealment   Not Applicable 
Blinding/Masking   Double Blind Double Dummy 
Primary Outcome  
Outcome  TimePoints 
Currently available mouthwashes in the market to maintain oral hygiene have side effects and are often expensive. Thus, the need of the study arises to recommend oral hygiene method to the community which is better safer and affordable alternative to mouthwashes.   baseline,3day and 7 days of follow up 
 
Secondary Outcome  
Outcome  TimePoints 
TRADITIONAL METHOD OF GARGLING  baseline 3day & 7 day 
 
Target Sample Size   Total Sample Size="125"
Sample Size from India="125" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   02/03/2026 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="0"
Months="8"
Days="0" 
Recruitment Status of Trial (Global)   Open to Recruitment 
Recruitment Status of Trial (India)  Open to Recruitment 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  

·       125 participants will be taken, subject will be randomly allocated into 5 groups using table of random numbers. Each group will be comprised of 25 study subjects.

Group 1: Coconut oil pulling

Group 2: Sesame oil pulling

Group 3: Olive oil pulling

Group 4: Chlorhexidine mouthwash

Group 5: Distilled water (placebo)

·       Subjects will be selected according to inclusion and exclusion criteria

·       Subjects will be advised to take 5-10 ml using a table spoon or till the mouth is half filled and sip, suck, pull the liquid through the teeth. Subjects will be advised to lift their chin a bit; close eyes and start swishing liquid from left to right, front to back approximately for 5-10 minutes or till the subjects feel fullness in mouth and the procedure will be performed prior to the brushing. The participants will be clearly instructed to take adequate precautions not to swallow the liquid while demonstrating the procedure. If at all swallowing occurs not to feel panic or fearful about the procedure.

·       Plaque levels will be measured using Turesky’s modification of the Quigley Hein Plaque Index, the condition of the gums will be assessed using the Loe and Silness Gingival Index and tongue coating will be measured using the Winkel Tongue Coating Index (WTCI).

·       Data collection will be done at baseline along with plaque, gingival and tongue coating index. Re-evaluate indices on 7th day and final evaluation of indices on 14th day. (ANNEXURE-F)

 
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