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CTRI Number  CTRI/2026/02/103546 [Registered on: 10/02/2026] Trial Registered Prospectively
Last Modified On: 11/02/2026
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Physiotherapy (Not Including YOGA) 
Study Design  Randomized, Parallel Group Trial 
Public Title of Study   Comparison of Exercises on Motion Sickness 
Scientific Title of Study   Comparison of Effects of Gaze Stability Exercises and Vestibular Habituation Exercises on Symptoms of Motion Sickness 
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
Modification(s)  
Name  Dr Sandeep Singh 
Designation  Head of Department and Assistant Professor 
Affiliation  Physiotherapy Department Punjabi Univeristy Patiala 
Address  Physiotherapy Department Punjabi University Patiala Punjab 147002 India

Patiala
PUNJAB
147002
India 
Phone  9417802490  
Fax    
Email  Sandeep.physiotherapy@pup.ac.in  
 
Details of Contact Person
Scientific Query

Modification(s)  
Name  Dr Sandeep Singh 
Designation  Head of Department and Assistant Professor 
Affiliation  Physiotherapy Department Punjabi University Patiala 
Address  Physiotherapy Department Punjabi University Patiala Punjab 147002 India

Patiala
PUNJAB
147002
India 
Phone  9417802490  
Fax    
Email  Sandeep.physiotherapy@pup.ac.in  
 
Details of Contact Person
Public Query
 
Name  Nehal  
Designation  Postgraduate student  
Affiliation  Physiotherapy Department Punjabi University Patiala 
Address  Physiotherapy Department Punjabi University Patiala Punjab 147002 India

Patiala
PUNJAB
147002
India 
Phone  9578160005  
Fax    
Email  nehalrampal10@gmail.com  
 
Source of Monetary or Material Support  
NIL 
 
Primary Sponsor  
Name  Nehal 
Address  Physiotherapy Department Punjabi University Patiala Punjab 147002 India 
Type of Sponsor  Other [Self] 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL  
 
Countries of Recruitment     India  
Sites of Study
Modification(s)  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr Sandeep Singh  Community Dwelling Adults   Next to Urban Estate Phase II Punjabi University Patiala Department of Physiotherapy Punjab 147002 India
Patiala
PUNJAB 
9417802490

Sandeep.physiotherapy@pup.ac.in 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Institutional Ethical Committee Punjabi University Patiala  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Healthy Human Volunteers  Individuals with Self-Reported Motion Sickness  
 
Intervention / Comparator Agent  
Type  Name  Details 
Intervention  Gaze Stability Exercises plus Neck Postural Stability Exercises  Gaze Stability Exercises will focus on vestibulo-ocular reflex (VOR) training using fixed visual targets. In Week 1, participants will focus on a stationary target while performing horizontal head movements for 1 minute × 5 repetitions with 1-minute rest between repetitions. In Week 2, both horizontal and vertical head movements will be added for 1 minutes × 5 repetitions. In Week 3, speed of head rotation will be progressively increased in both directions for 1 minutes × 5 repetitions. Sessions will be conducted 4 days per week for a total duration of 3 weeks where Neck Postural Stability Exercises will be identical to the comparator group and will include deep cervical flexor strengthening (10 repetitions with 10-second hold, 2 sets), isometric neck contractions in all directions (10 repetitions with 10 second hold, 2 sets), and cervical proprioception training using laser pointer tracking (10 repetitions with 2 sets). Total session duration of Gaze Stability Exercises along Neck Postural Stability Exercises will take 50 minutes. 
Comparator Agent  Vestibular Habituation Exercises plus Neck Postural Stability Exercises  Vestibular Habituation Exercises will include graded eye–head coordination and motion desensitization tasks. In Week 1, participants will perform eye movements with head and target stationary and eye–target movements with head stationary for 1 minute × 5 repetitions each, followed by 1minute rest between repetitions. In Week 2, head movement with eyes fixed on a stationary target will be performed for 1 minute × 5 repetitions each with 1minute rest between repetitions In Week 3, coordinated eye, head, and target movements will be performed for 1minute × 5 repetitions with 1minute rest between repetitions. Sessions will be conducted 4 days per week for a total duration of 3 weeks. Neck Postural Stability Exercises will be administered in all sessions and will include deep cervical flexor training (chin tuck against wall – 10 repetitions with 10-second hold, 2 sets), isometric neck exercises in all directions (10 repetitions with 10 second hold, 2 sets), and cervical proprioception training using laser pointer tracking (10 repetitions with 2 sets). Total session duration of Vestibular Habituation Exercises along Neck Postural Stability Exercises will take 50 minutes. 
 
Inclusion Criteria  
Age From  18.00 Year(s)
Age To  38.00 Year(s)
Gender  Both 
Details  Individuals Aged- 18 to 38 years
Both males and females.
Individuals having history of motion sickness
Individuals reporting motion related symptoms such as drowsiness, reduced alertness,
cold sweats, pallor, excessive salivation, headaches, nausea, vomiting dizziness during
travel (e.g., bus, car, train, boat, and airplane) or during funfair rides and virtual reality 
 
ExclusionCriteria 
Details  Individuals having history of vestibular dysfunction or neurological disorders
Having visual or hearing impairment
Undergoing any medical or other treatment for motion sickness
Having history of migraines, seizure disorder 
 
Method of Generating Random Sequence   Coin toss, Lottery, toss of dice, shuffling cards etc 
Method of Concealment   Other 
Blinding/Masking   Not Applicable 
Primary Outcome  
Outcome  TimePoints 
Motion Sickness Assessment Questionnaire (MSAQ)
Stimulator Sickness Questionnaire (SSQ) 
At the baseline and end of 3rd week 
 
Secondary Outcome  
Outcome  TimePoints 
Neck Disability Index (NDI)  At the baseline and end of 3rd week  
 
Target Sample Size   Total Sample Size="32"
Sample Size from India="32" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   16/03/2026 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="0"
Months="6"
Days="0" 
Recruitment Status of Trial (Global)   Not Applicable 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  

Motion sickness is a common sensory–vestibular disorder, leading to symptoms such as nausea, dizziness, headache, fatigue, postural instability, and reduced functional performance. These symptoms arise due to sensory conflict between visual, vestibular, and proprioceptive inputs, particularly during travel and virtual reality exposure. Physiotherapy approaches such as Gaze Stability Exercises (GSE) and Vestibular Habituation Exercises (VHE) have shown promising outcomes in reducing motion sensitivity and improving balance. Neck Postural Stability Exercises (NPSE) further enhance cervical proprioception and neuromuscular control, contributing to better sensory integration.

This study aims to compare the effectiveness of Gaze Stability Exercises and Vestibular Habituation Exercises administered along with Neck Postural Stability Exercises in reducing symptoms of motion sickness.

An experimental randomized controlled trial design will be employed, comprising 32 participants aged 18–38 years with moderate level motion sickness. Participants will be randomly allocated into two groups based on predefined inclusion and exclusion criteria. Group A will receive Gaze Stability Exercises plus Neck Postural Stability Exercises, while Group B will receive Vestibular Habituation Exercises plus Neck Postural Stability Exercises. The intervention protocol will be administered four sessions per week for three weeks. Outcome measures including MSAQ, SSQ, and NDI will be recorded at baseline and post-intervention following controlled VR exposure. Statistical analysis will be conducted using appropriate methods to determine the significance of findings.

The study intends to propose a cost-effective, safe, non-pharmacological, and evidence-based physiotherapeutic approach for the management of motion sickness. Ethical considerations will be strictly followed, and written informed consent will be obtained from all participants prior to study initiation.

 
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